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NCT05896826Recruiting

Magnetocardiography in the Accurate Identification of Myocardial Infarction

Ultra-sensitive Magnetocardiography in the Accurate Identification of Myocardial Infarction

Source: ClinicalTrials.gov · Last updated 2 Oct 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

Magnetocardiography (MCG) is a promising noninvasive and accurate method for detecting myocardial infarction. Although progress has been made in this area, there is a lack of studies using up-to-date examination instruments for the calibration of MCG analysis. This is a prospective single-center study aiming to build accurate analytical models of MCG to detect myocardial infarction. Myocardial infarction are diagnosed by electrocardiogram, biomarkers (high-sensitivity cardiac troponin, etc), or non-invasive imaging (cardiac magnetic resonance or single-photon-emission tomography). Myocardial infarction is also quantified by cardiac magnetic resonance or single-photon-emission tomography. Healthy volunteers and chest pain patients who will receive electrocardiogram, biomarkers (high-sensitivity cardiac troponin, etc), or non-invasive imaging (cardiac magnetic resonance or single-photon-emission tomography) examination will be enrolled in this study.

Status (registry)
Recruiting
Study type
Observational
Enrollment
3841 (estimated)
First submitted
31 May 2023
Start date
1 Jun 2023
Primary completion date
31 Oct 2025
Lead sponsor
Qilu Hospital of Shandong University
NCT number
NCT05896826

What you commit to

  • Study type: Observational
  • Planned participants: 3841
  • From 1 Jun 2023 to the primary completion date, 31 Oct 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Those who with acute or chronic respiratory diseases;
  • Those who with endocrine diseases such as abnormal thyroid function;
  • Those who with anemia or other blood diseases;
  • Those who with connective tissue diseases (lupus erythematosus, rheumatoid arthritis, dermatomyositis, polyarteritis nodosa, etc.);
  • Those who with malignant tumors;
  • Those who with infectious diseases or infectious diseases;
  • Those who with psychological or mental illness such as depression;
  • Due to various reasons such as allergy to contrast agents, metal implants in vivo that are prohibited from performing 1.5T MRI (such as prostheses or steel plates implanted in orthopaedics, uterine contraceptive device) and other reasons, those who cannot or fail to cooperate with the corresponding research requirements.
    • For chest pain patients who will receive ECG, biomarkers, or non-invasive imaging examination:
  • Patients with known structural heart disease such as cardiomyopathy and valvular disease;
  • Patients with arrhythmias such as atrial fibrillation, supraventricular tachycardia, and atrioventricular block that have not returned to normal;
  • History of other cardiovascular diseases such as pulmonary embolism and aortic dissection;
  • Patients with connective tissue diseases (lupus erythematosus, rheumatoid arthritis, dermatomyositis, polyarteritis nodosa, etc.) combined with cardiac complications;
  • Obvious abnormal thyroid function, severe anemia or other blood diseases and other diseases that obviously affect the circulating blood supply;
  • Patients with malignant tumors;
  • Acute diseases or critical illnesses in other systems, such as acute or severe respiratory diseases, abnormal liver function or renal function, etc.;
  • Patients with infectious diseases or infectious diseases;
  • Those who are unable or fail to perform magnetocardiography due to claustrophobia, physical impairment, etc.;

Other

  • Those who with obvious abnormality of liver or kidney function;
  • Those who are obese (BMI\>30kg/cm2) or underweight (BMI\<18kg/cm2);
  • Those who with trauma or physical disability;
  • Those who are professional athletes, pregnant or breastfeeding women, alcoholics;
  • Those who are unable to perform magnetocardiography examination due to claustrophobia, etc., or those who fail to receive magnetocardiography examination;
  • Obese (BMI\>30kg/cm2) or underweight (BMI\<18kg/cm2);
  • Professional athletes, pregnant or breastfeeding women, alcoholics;
  • Unable to or fail to cooperate with the corresponding research requirements.

Who the study is looking for

  • Age 18-79 years old;
  • No history of cardiovascular disease (coronary heart disease, structural heart disease, arrhythmia, heart failure, stroke, pulmonary embolism, aortic dissection, etc.), no cardiovascular risk factors (hypertension, diabetes, hyperlipidemia). For people over 65 years old, those with hypertension or hyperlipidemia, but with well-controlled blood pressure and lipid levels, taking no more than 2 drugs, and echocardiography showing no left ventricular hypertrophy, can be included;
  • The electrocardiogram is normal, and the cardiac ultrasound is basically normal in the past 1 year (mild valvular regurgitation can be included).
  • Sign the informed consent.
  • Age 18-79 years old;
  • Those with chest pain symptoms, diagnosed or highly suspected by the attending doctor or above as stable angina pectoris (SA), unstable angina pectoris (UA), non-ST segment elevation myocardial infarction (NSTEMI), ST segment elevation myocardial infarction (STEMI), and plan to receive electrocardiogram, biomarkers (high-sensitivity cardiac troponin, etc), or non-invasive imaging (cardiac magnetic resonance or single-photon-emission tomography);
  • Sign the informed consent.

Criteria the registry did not label

  • For healthy volunteers:

Age in the registry: 18 years to 79 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Qilu Hospital of Shandong University
Coordinator of this site? Confirm its status
JinanChinaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.