Fact CheckerSign in

NCT05899439Recruiting

Immune Function and the Progression to T1D

Immune Function and the Progression to Type 1 Diabetes:

Source: ClinicalTrials.gov · Last updated 9 Apr 2026

Brief summary (registry, in English)

To elucidate the mechanisms by which type 1 diabetes-associated genes; IFIH1, TYK2, IKZF4, as well as total genetic risk, impart functional immunoregulatory abnormalities that result in expansion of self-reactive adaptive immune cells, defective regulatory/effector mechanisms in T cells, inflammatory antigen presenting cells, and abnormal immune function in T cells and B cells.

Status (registry)
Recruiting
Study type
Observational
Enrollment
2800 (estimated)
First submitted
22 May 2023
Start date
1 Jan 2005
Primary completion date
1 Jan 2085
Lead sponsor
University of Florida
NCT number
NCT05899439

What you commit to

  • Study type: Observational
  • Planned participants: 2800
  • From 1 Jan 2005 to the primary completion date, 1 Jan 2085
  • 3 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • \-

Age in the registry: 0 years to 100 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (3)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
The Ohio State University
Coordinator of this site? Confirm its status
ColumbusUnited StatesRecruiting
Kieran McGrail
Coordinator of this site? Confirm its status
GainesvilleUnited StatesRecruiting
Baylor College of Medicine, Center for Research Advancement - Texas Children's Hospital
Coordinator of this site? Confirm its status
HoustonUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.