NCT05899439Recruiting
Immune Function and the Progression to T1D
Immune Function and the Progression to Type 1 Diabetes:
Source: ClinicalTrials.gov · Last updated 9 Apr 2026
Brief summary (registry, in English)
To elucidate the mechanisms by which type 1 diabetes-associated genes; IFIH1, TYK2, IKZF4, as well as total genetic risk, impart functional immunoregulatory abnormalities that result in expansion of self-reactive adaptive immune cells, defective regulatory/effector mechanisms in T cells, inflammatory antigen presenting cells, and abnormal immune function in T cells and B cells.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 2800 (estimated)
- First submitted
- 22 May 2023
- Start date
- 1 Jan 2005
- Primary completion date
- 1 Jan 2085
- Lead sponsor
- University of Florida
- Diseases
- Type 1 diabetes
- NCT number
- NCT05899439
What you commit to
- Study type: Observational
- Planned participants: 2800
- From 1 Jan 2005 to the primary completion date, 1 Jan 2085
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- \-
Age in the registry: 0 years to 100 years · Sex: All · Accepts healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Ohio State University Coordinator of this site? Confirm its status | Columbus | United States | Recruiting |
| Kieran McGrail Coordinator of this site? Confirm its status | Gainesville | United States | Recruiting |
| Baylor College of Medicine, Center for Research Advancement - Texas Children's Hospital Coordinator of this site? Confirm its status | Houston | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.