NCT05904327Active, not recruiting
Circulating Biomarkers in Oropharyngeal Cancers
The Use of Circulating Biomarkers in Oropharyngeal Cancer and Unknown Primary of Head and Neck - a Prospective Multicenter Study for Treatment Evaluation and Surveillance
Source: ClinicalTrials.gov · Last updated 15 Jun 2023
Brief summary (registry, in English)
The goal of this observational longitudinal study is to learn about circulating tumor Human Papilloma Virus-DNA (ctHPV-DNA) as a biomarker for HPV positive oropharyngeal cancer and cancer of unknown primary of the head and neck. The main questions it aims to answer are: * Can ctHPV-DNA be used for treatment evaluation in HPV positive oropharyngeal cancer and cancer of unknown primary of the head and neck? * Can circulating HPV-DNA be used as a biomarker for recurrent disease during surveillance? Participants will be asked to leave plasma samples at diagnose, at the end of treatment and at every clinical follow-up. The patients are there own controls.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 130 (actual)
- First submitted
- 17 Apr 2023
- Start date
- 1 Dec 2020
- Primary completion date
- 31 Mar 2028
- Lead sponsor
- Region Örebro County
- Diseases
- Head and neck cancer, Childhood cancers
- NCT number
- NCT05904327
What you commit to
- Study type: Observational
- Participants enrolled: 130
- From 1 Dec 2020 to the primary completion date, 31 Mar 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous treatment of cancer in the oropharynx.
- Previous treatment of unknown primary tumor.
Other
- Remote metastases
- Patients unwilling or unable to comply with the study protocol and follow-up schedule
Who the study is looking for
- Oropharyngeal cancer
- Cancer of unknown primary in the head and neck
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Anna Oldaeus Almerén Coordinator of this site? Confirm its status | Örebro | Sweden | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.