NCT05905705Recruiting
Disruptions of Brain Networks and Sleep by Electroconvulsive Therapy
Source: ClinicalTrials.gov · Last updated 12 Mar 2026
Brief summary (registry, in English)
Electroconvulsive therapy (ECT) alleviates treatment-resistant depression (TRD) through repeated generalized seizures. The goal of this study is to evaluate how ECT impacts sleep-wake regulation and efficiency of information transfer in functional networks in different states of arousal.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 50 (estimated)
- First submitted
- 6 Jun 2023
- Start date
- 7 Mar 2023
- Primary completion date
- 31 Jul 2027
- Lead sponsor
- Washington University School of Medicine
- Diseases
- Depression
- NCT number
- NCT05905705
What you commit to
- Study type: Observational
- Planned participants: 50
- From 7 Mar 2023 to the primary completion date, 31 Jul 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Diagnoses of schizophrenia or schizoaffective disorders.
Other
- Subjects who are unable to tolerate the Dreem device for sleep recordings will be excluded from the study.
Who the study is looking for
- Referral for initial ECT index course for Treatment-Resistant Depression (TRD), unipolar major depressive disorder or bipolar depression. Historic failure of response or remission to at least two antidepressant medications of sufficient dose and duration will be used for TRD diagnostic.
Age in the registry: 21 years to 65 years · Sex: All
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Washington University School of Medicine/Barnes-Jewish Hospital Coordinator of this site? Confirm its status | St Louis | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.