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NCT05906420Active, not recruiting

Posterior Circulation ASTRAL Prognostic Score

Pc-ASTRAL Score for the Prediction of 3 Months Functional Outcome in Acute Ischemic Stroke at the Posterior Circulation

Source: ClinicalTrials.gov · Last updated 8 Apr 2025

Brief summary (registry, in English)

The goal of this study is to develop a prognostic score for ischemic posterior circulation strokes, based on our previous work on with the ASTRAL scores (Acute STroke Registry and Analysis of Lausanne) on overall stroke prognosis, intracranial occlusion, recanalization and stroke recurrences. The main question it aims to answer is the modified Rankin score in 3 months after the event. Participants will be patients with acute ischemic stroke of the posterior circulation with mRS priot to event \<3. All the data will be collected retrospectively from patients included in the ASTRAL registry between January 2003 and December 2021. The ASTRAL registry will be used as the derivation cohort of the score. Demographics, acute glucose, NIHSS score and acute imaging of each participant will be used from the derivation cohort in order to create an integer-based prognostic score. After internal validation, we plan to validate the score in external stroke registries to show its validity.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
2000 (estimated)
First submitted
6 Jun 2023
Start date
1 Jan 2003
Primary completion date
31 Dec 2021
Lead sponsor
University of Thessaly
Diseases
Stroke
NCT number
NCT05906420

What you commit to

  • Study type: Observational
  • Planned participants: 2000
  • From 1 Jan 2003 to the primary completion date, 31 Dec 2021
  • 2 sites in 2 countries
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • modified Rankin Score≥3 prior the event

Other

  • no available data for 3 months modified Rankin Score

Who the study is looking for

  • Isolated posterior circulation strokes based on clinical or/and imaging evidence.
  • Arriving within 24h at hospital since last proof of good health.

Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (2)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Stroke Center, Department of clinical neurosciences, Lausanne University Hospital and University of Lausanne
Coordinator of this site? Confirm its status
LausanneSwitzerlandUnknown status
First Propedeutic Department of Internal Medicine & Stroke Unit, AHEPA University Hospital, Aristotle University of Thessaloniki
Coordinator of this site? Confirm its status
ThessalonikiGreeceUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.