NCT05909189Active, not recruiting
LEADing Dementia End-of-Life Planning Conversations
Source: ClinicalTrials.gov · Last updated 10 Jul 2026
Brief summary (registry, in English)
Advance care planning is important for all adults, but perhaps even more so for the 5.7 million persons with Alzheimer's disease or related dementia (ADRD), due to the progressive and protracted cognitive deterioration associated with the disease process. In the context of ADRD, medical decision-making at the end of life is typically left to one's care partner, who often does not have the knowledge or confidence in their ability to make such decisions. This study will refine and evaluate a web-based platform, called the LEAD Intervention (Life-Planning in Early Alzheimer's and other Dementias), which is designed to help persons in the preclinical or early stage of ADRD engage in conversations about, document, and share their end-of-life values and preferences with a care partner, extended family members, and health care providers.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 120 (estimated)
- First submitted
- 12 May 2023
- Start date
- 4 Aug 2024
- Primary completion date
- 31 May 2027
- Lead sponsor
- University of Utah
- Diseases
- Alzheimer disease
- NCT number
- NCT05909189
What you commit to
- Study type: Interventional
- Planned participants: 120
- From 4 Aug 2024 to the primary completion date, 31 May 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Has moderate to severe symptoms of dementia
Who the study is looking for
- Care Recipient (CR) is age 50+
- CR Is interested in having conversations about and documenting wishes for future end-of-life care
- CR has noticed changes in memory or thinking skills indicative of preclinical or early stage of AD, OR
- CR has been diagnosed with mild cognitive impairment, Alzheimer's disease, or another type of dementia and in the preclinical or early stage
- Care Partner (CP) is age 18+
- CP is a Spouse/partner, family member, or close friend of CR
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Utah College of Nursing Coordinator of this site? Confirm its status | Salt Lake City | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.