NCT05917132Completed
Production of Gut Microbiota-Derived Metabolites in Response to Different Fatty Acid Profiles
Source: ClinicalTrials.gov · Last updated 27 Jun 2025
Brief summary (registry, in English)
The proposed project mainly aims to investigate the microbial processes leading to dietary metabolites production, independently of long-term microbiota adaptation to the diet, by measuring the microbiota-derived metabolite production from a meal sequence rich in saturated fatty acids (SFA) or the same meals but rich in polyunsaturated fatty acids (PUFA) in individuals with or without obesity and Type 2 diabetes (T2D)
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 49 (actual)
- First submitted
- 15 Jun 2023
- Start date
- 12 Jun 2023
- Primary completion date
- 31 May 2024
- Lead sponsor
- Laval University
- Diseases
- Obesity, Type 2 diabetes
- NCT number
- NCT05917132
What you commit to
- Study type: Interventional
- Participants enrolled: 49
- From 12 Jun 2023 to the primary completion date, 31 May 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Consumption of dietary supplements (vitamins and probiotics) - must be ceased 2 weeks before the dietary intervention ;
Other illness
- Intestinal pathologies including inflammatory bowel disease and gastrointestinal cancers ;
- Type 1 diabetes or insulin-treated diabetes.
Other
- Alcohol consumption greater than 15 portions for men and 10 for women weekly.
- Active tobacco and cannabis usage ;
- Consumption of omega-3 dietary supplements ;
- Completion of a course of antibiotics in the past 3 months ;
- Important weight change (+/- 5 kg) in the past 6 months ;
Who the study is looking for
- Men and women aged between 45 and 65 years, menopaused women ;
- Body mass index between 20 to 35 kg/m² ;
- General good health ;
- Score of diet quality (HEI) between 40 and 70 ;
- Computer and Internet access ;
- Basic understanding of written French ;
- Daily stool frequency.
Age in the registry: 45 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Institut sur la nutrition et les aliments fonctionnels - INAF Coordinator of this site? Confirm its status | Québec | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.