NCT05918380Active, not recruiting
Project 3: ACHIEVE- CHD
ACHIEVE GREATER: Addressing Cardiometabolic Health In Populations Through Early Prevention in the Great Lakes Region
Source: ClinicalTrials.gov · Last updated 28 Aug 2026
Brief summary (registry, in English)
This project is part of the ACHIEVE GREATER (Addressing Cardiometabolic Health In Populations Through Early Prevention in the Great Lakes Region) Center (IRB 100221MP2A), the purpose of which is to reduce cardiometabolic health disparities and downstream Black-White lifespan inequality in two cities: Detroit, Michigan, and Cleveland, Ohio. The ACHIEVE GREATER Center will involve three separate but related projects that aim to mitigate health disparities in risk factor control for three chronic conditions, hypertension (HTN, Project 1), heart failure (HF, Project 2) and coronary heart disease (CHD, Project 3), which drive downstream lifespan inequality. All three projects will involve the use of Community Health Workers (CHWs) to deliver an evidence-based practice intervention program called PAL2. All three projects will also utilize the PAL2 Implementation Intervention (PAL2-II), which is a set of structured training and evaluation strategies designed to optimize CHW competence and adherence (i.e., fidelity) to the PAL2 intervention program. The present study is Project 3 of the ACHIEVE GREATER Center.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 500 (estimated)
- First submitted
- 5 Jun 2023
- Start date
- 15 Aug 2022
- Primary completion date
- 1 Jan 2027
- Lead sponsor
- University Hospitals Cleveland Medical Center
- Diseases
- Coronary artery disease
- NCT number
- NCT05918380
What you commit to
- Study type: Interventional
- Planned participants: 500
- From 15 Aug 2022 to the primary completion date, 1 Jan 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Individuals receiving treatment for cancer related disease
Other illness
- Established documented cardiovascular disease (coronary artery disease, peripheral artery disease, myocardial infarction, stroke).
- Lung disease requiring supplemental oxygen therapy
Other
- Systolic blood pressure ≥ 180 mmHg or diastolic blood pressure ≥ 110 mmHg
- Pregnant or nursing mothers
Who the study is looking for
- 40 to 75 years of age
- Self-identified as Black or African American
- Residence in the Cleveland Metro Area
- Must have at least two of the following risk factors identified at a UH health fair screenings, with one risk factor being with SBP, A1c, or LDL:
- BMI≥30 mg/dL
- History of smoking
- Elevated blood pressure defined as SBP\>140 or DBP\>80 mmHg
- HbA1c≥5.7%
- LDL≥130
- Able to complete a coronary artery calcium score test (CAC)
- Willing and able to consent
- Willing to have a UH provider and UH care
- Currently insured for standard of care procedures
Age in the registry: 40 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospitals Cleveland Medical Center* Coordinator of this site? Confirm its status | Cleveland | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.