NCT05920616Completed
Comprehensive Imaging Exam of Convalesced COVID-19 Patients
Source: ClinicalTrials.gov · Last updated 10 Jun 2026
Brief summary (registry, in English)
COVID-19 is a systemic inflammatory disease involving many organs including the lungs, vascular system liver and myocardium that lead to severe pathologies. Patients with severe cardiopulmonary symptoms usually require weeks to months to fully recover. Studies of clinical and subclinical impairments of COVID-19 patients are important for medical practice and public health as well as providing pathogenic insight to the viral infection and secondary immune response. Chronic damage of vital organs and systems, and the potential long-term effects is of serious concern. In this study the investigators plan to quantify and characterize chronic consequences of COVID-19 in individuals who receive similar medical care related to disease severity and duration in a single health care system. Using state-of-the-art Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) technology, we will study the pathology in major organ systems in comparison to matched controls. The results of this study may facilitate measures to prevent, detect, and manage complications from COVID-19 infections.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 206 (actual)
- First submitted
- 23 Jun 2023
- Start date
- 14 Oct 2020
- Primary completion date
- 15 May 2026
- Lead sponsor
- Johns Hopkins University
- NCT number
- NCT05920616
What you commit to
- Study type: Interventional
- Participants enrolled: 206
- From 14 Oct 2020 to the primary completion date, 15 May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Internal electrical devices, such as cochlear implant, spinal cord stimulator, pacemaker, or defibrillator
Other illness
- Known allergy to either gadolinium or iodine based contrast agents
- Evidence of severe symptomatic heart failure (NYHA Class III or IV) at the time of imaging
- Other acute illness
- Ongoing mechanical ventilation related to hospitalization for COVID-19 related illness
- Presence of any other history or condition that the investigator feels would be problematic
Lab values
- Glomerular Filtration Rate (GFR) \<45 mL/min (using the Cockcroft-Gault formula)
Other
- Pregnancy
- Atrial fibrillation, uncontrolled tachyarrhythmia or advanced atrioventricular block (2nd or 3rd degree) at time of imaging
- Weight exceeding 300 lbs (MRI table weight restrictions)
- Severe claustrophobia
Who the study is looking for
- Age: 18+
- Diagnosed with COVID-19 at any point starting March 2020.
- Subgroup A: hospitalized due to COVID-19 infection
- Subgroup B: non-hospitalized
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Johns Hopkins School of Medicine Coordinator of this site? Confirm its status | Baltimore | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.