NCT05920694Active, not recruiting
Restoring Metabolic and Reproductive Health With Sleep in PCOS Study, CPAP Trial
Source: ClinicalTrials.gov · Last updated 23 Jan 2026
Brief summary (registry, in English)
In this study, the researchers are trying to learn more about the relationship between Polycystic Ovary Syndrome and Obstructive Sleep Apnea (OSA). Obstructive Sleep Apnea is a sleep-related breathing disorder that involves a decrease or complete stop in airflow. The purpose of this study is to find out why some people with obstructive sleep apnea have higher levels of insulin resistance, and the investigators will study the role of hypoxia (low levels of oxygen in the blood at night) in insulin resistance and see if insulin resistance improves during your treatment with CPAP.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 5 Jun 2023
- Start date
- 22 Dec 2022
- Primary completion date
- 30 Jul 2026
- Lead sponsor
- University of California, San Francisco
- NCT number
- NCT05920694
What you commit to
- Study type: Interventional
- Planned participants: 20
- From 22 Dec 2022 to the primary completion date, 30 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior OSA treatment
Other illness
- HIV infection or infectious hepatitis
- Excessive daytime sleepiness as defined as \>16 on the Eppworth Sleepiness Scale or untreated or inadequately treated hypertension (\>150/90)
Lab values
- Diabetes mellitus (fasting glucose ≥126 mg/dL or 2-h glucose ≥200 mg/dL or HGB A1c ≥6.5%)
Other
- Current use of oral contraceptives
- Treatment for asthma
- Regular tobacco use or alcohol consumption exceeding 1 drink/day
- Pregnancy or lactation within the past six months
Who the study is looking for
- Subjects found to have moderate to severe OSA (AHI \>15)
- PCOS diagnosis satisfies both the hyperandrogenic and oligo-ovulatory requirements of Rotterdam criteria
- Ages 18-40
- BMI 25-45 kg/m2
- Fasting insulin \>16
- At-risk score on Berlin Questionnaire
Age in the registry: 18 years to 40 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of California San Francisco Coordinator of this site? Confirm its status | San Francisco | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.