NCT05923359Active, not recruiting
Realtime Diagnosis From Electrocardiogram Artificial Intelligence-Guided Screening for Atrial Fibrillation With Long Follow-Up (REGAL)
Source: ClinicalTrials.gov · Last updated 13 Oct 2026
Brief summary (registry, in English)
The purpose of this research is to test whether Apple Watch, used as a long-term monitoring device, can enable early detection of atrial fibrillation.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 2000 (estimated)
- First submitted
- 19 Jun 2023
- Start date
- 10 Apr 2024
- Primary completion date
- 31 Mar 2028
- Lead sponsor
- Mayo Clinic
- Diseases
- Atrial fibrillation
- NCT number
- NCT05923359
What you commit to
- Study type: Interventional
- Planned participants: 2000
- From 10 Apr 2024 to the primary completion date, 31 Mar 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Diagnosed dementia
- Diagnosed end-stage kidney disease
- History of intracranial bleeding
- Have an implantable cardiac monitoring device, including a pacemaker, a defibrillator, or implanted loop recorder
Other
- Diagnosed atrial fibrillation
- Missing date of birth
- Residence outside of the U.S. or missing address information
Who the study is looking for
- Had a 10-second 12-lead ECG done at Mayo Clinic
- Have a high AI-ECG risk score indicating a high likelihood of previously unrecognized AF
- Men with CHA2DS2-VASc2 ≥2 or women with CHA2DS2-VASc ≥ 3
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mayo Clinic Coordinator of this site? Confirm its status | Rochester | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.