NCT05924971RecruitingPhase 2
Aspirin for Postpartum Patients With Preeclampsia
Acetylsalicylic Acid for Postpartum Preeclampsia: A Pilot Randomized Trial
Source: ClinicalTrials.gov · Last updated 6 Jun 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The purpose of this research study is to evaluate the effect of low-dose aspirin on recovery from severe preeclampsia (a high blood pressure disorder of pregnancy) among women who have given birth. We hypothesize that taking aspirin for the first week after giving birth will enhance recovery from preeclampsia by decreasing the levels of a protein called soluble fms-like tyrosine kinase (sFlt-1), which is thought to be a main contributor to the development of preeclampsia, and speeding up return to a normal blood pressure.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 86 (estimated)
- First submitted
- 21 Jun 2023
- Start date
- 26 Jul 2023
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- MemorialCare Health System
- NCT number
- NCT05924971
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 86
- From 26 Jul 2023 to the primary completion date, 31 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Known allergy, prior adverse reaction, or any medical condition in which aspirin is contraindicated (nasal polyps, gastric or duodenal ulcers, history of gastrointestinal bleeding, severe hepatic dysfunction)
Other illness
- Chronic hypertension diagnosed before 20 weeks' gestation
- Aspirin prescribed postpartum for any other medical condition
- Bleeding disorder
Age
- Patient age \<18 years old
Other
- Non-English or Non-Spanish speaking
- Breastfeeding an infant with thrombocytopenia
Who the study is looking for
- Preeclampsia with severe features diagnosed during delivery admission, as defined by ACOG criteria.
- Pre- and postnatal care provided by the Long Beach Memorial Ob/Gyn resident or Maternal-Fetal Medicine clinic.
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Miller Children's and Women's Hospital, Long Beach/MemorialCare Long Beach Coordinator of this site? Confirm its status | Long Beach | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.