NCT05925569Active, not recruiting
Electronic Alert to Improve Testing For Primary Aldosteronism in Patients With Hypertension
Electronic Alert-Based Computerized Decision Support to Improve Testing For Primary Aldosteronism in Patients With Hypertension: ALERT-PA
Source: ClinicalTrials.gov · Last updated 3 Nov 2026
Brief summary (registry, in English)
Primary aldosteronism (PA) is common but rarely recognized cause of hypertension that carries excess cardiovascular and renal risk and has approved targeted treatments. Despite current clinical guidelines that recommend screening in a defined set of high-risk populations, less than 5% of eligible patients are ever screened for PA. This study aims to evaluate the impact of a computer decision support Best Practice Advisory (BPA) alert on rates of screening for PA in guideline-eligible patients, referral to specialist PA care, and treatment with mineralocorticoid receptor antagonists.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 12501 (actual)
- First submitted
- 22 Jun 2023
- Start date
- 13 Mar 2024
- Primary completion date
- 9 Dec 2024
- Lead sponsor
- Brigham and Women's Hospital
- Diseases
- High blood pressure
- NCT number
- NCT05925569
What you commit to
- Study type: Interventional
- Participants enrolled: 12501
- From 13 Mar 2024 to the primary completion date, 9 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of Primary Aldosteronism (ICD Code)
Other
- Prescription for a Mineralocorticoid Receptor Antagonist (MRA) within the last 3 months
Who the study is looking for
- Adults 18+
- Seen by clinician at one of the intervention practices at least once in the prior 2 years
- History of Hypertension (ICD Code) PLUS ≥1 of the below:
- Outpatient BP \>150/100 on 2 or more occasions
- Three or more current antihypertensive medication prescriptions
- Potassium level \<3.5mEq/L or potassium supplement prescription in the last 5 years
- History of Atrial Fibrillation or Atrial Flutter (ICD Code)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Brigham and Women's Hospital Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.