NCT05929911Recruiting
Open Trial of Trauma-focused Psychodynamic Psychotherapy for People Living With HIV and PTSD
Pilot Feasibility Proposal to Adapt Trauma-focused Psychodynamic Psychotherapy (TFPP) for PLWH and PTSD
Source: ClinicalTrials.gov · Last updated 12 Jun 2026
Brief summary (registry, in English)
People living with HIV (PLWH) have a higher rate of post-traumatic stress disorder (PTSD) diagnosis than the general population. Comorbid PTSD is also associated with negative HIV-related health outcomes. Unfortunately, little outcome research has examined the usefulness of PTSD treatments for PTSD. This pilot study adapts for PLWH a non-exposure based psychotherapy for PTSD focused on reflecting on one's emotions and relationships and understanding and working through how trauma may have disrupted them. The study team is interested in better understanding the needs of PLWH with PTSD, learning whether PLWH with PTSD find this treatment acceptable and helpful, and beginning to understand the relationship between HIV-related health factors (e.g., inflammation and stress biology) and PTSD, and how these health factors may improve during treatment.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 23 Jun 2023
- Start date
- 26 Apr 2024
- Primary completion date
- 30 Jun 2027
- Lead sponsor
- Montefiore Medical Center
- Diseases
- HIV
- NCT number
- NCT05929911
What you commit to
- Study type: Interventional
- Planned participants: 20
- From 26 Apr 2024 to the primary completion date, 30 Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Current substance use disorder
- Organic mental syndrome or intellectual disability
- Unstable non-HIV medical conditions
Other
- Psychosis
- Bipolar I
- Acute suicidality
Who the study is looking for
- Diagnosis of DSM-5 defined PTSD, per the Clinician Administered PTSD Scale \& CAPS-5 total severity score greater than or equal to 25
- HIV diagnosis (by medical records or HIV testing)
- Stable psychiatric/psychotropic medication for \>=2 months and ongoing during treatment
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Albert Einstein College of Medicine Coordinator of this site? Confirm its status | The Bronx | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.