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NCT05932485Completed

Effect of Stellate Ganglion Block on New Atrial Fibrillation After Coronary Artery Bypass Grafting

Source: ClinicalTrials.gov · Last updated 22 Dec 2025

Brief summary (registry, in English)

Post-operative new-onset atrial fibrillation (POAF) is one of the most common arrhythmias in adults after direct intracardiac surgery with extracorporeal circulation. The incidence of POAF in coronary artery bypass grafting (CABG) is approximately 30%. POAF can lead to an increased risk of complications such as stroke, heart failure, and acute kidney injury, which not only prolongs the patient's hospital stay, but also increases hospital costs and mortality. operation, extracorporeal circulation, and the patient's underlying conditions (such as age, gender, hypertension, and diabetes), which cause sympathetic activation, inflammatory response, and myocardial ischemia in the organism. The stellate ganglion block (SGB) regulates the sympathetic tone of the innervated nerves and thus the autonomic function of the body. SGB can effectively regulate the sympathetic-parasympathetic imbalance. Also, SGB may exert some anti-inflammatory effects. In this study, ultrasound-guided SGB was used in CABG patients to investigate its effect on the occurrence of POAF.

Status (registry)
Completed
Study type
Interventional
Enrollment
108 (actual)
First submitted
10 Jun 2023
Start date
1 Jun 2023
Primary completion date
1 Jun 2024
Lead sponsor
Yangzhou University
NCT number
NCT05932485

What you commit to

  • Study type: Interventional
  • Participants enrolled: 108
  • From 1 Jun 2023 to the primary completion date, 1 Jun 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Surgical procedures include any other type of heart surgery in addition to CABG;
  • Allergic to known general anesthesia drugs;
  • Patients with a history of neck surgery or abnormal neck anatomy;

Other

  • The patient refused to participate in this study;
  • Patients with contraindications to SGB.

Who the study is looking for

  • Patients undergoing first-time and elective coronary artery bypass grafting;
  • ASA grade II-IV;
  • The preoperative ECG showed sinus heart rate.

Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
the Affiliated Hospital of Yangzhou University, Yangzhou University
Coordinator of this site? Confirm its status
YangzhouChinaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.