NCT05938699CompletedPhase 2/3
Aqueous Humor Dynamics of NCX 470 Ophthalmic Solution
Aqueous Humor Dynamics of NCX 470 Ophthalmic Solution - A Double-Masked, Placebo-Controlled, Phase 3b Clinical Trial (Whistler)
Source: ClinicalTrials.gov · Last updated 8 Sept 2025
Brief summary (registry, in English)
This is a double-masked, placebo-controlled study which will determine the action of NCX 470 ophthalmic solution, 0.1% on aqueous humor dynamic parameters in healthy volunteers or subjects with OHT.
- Status (registry)
- Completed
- Phase (registry)
- Phase 2/3
- Study type
- Interventional
- Enrollment
- 18 (actual)
- First submitted
- 15 Jun 2023
- Start date
- 12 Dec 2023
- Primary completion date
- 17 Mar 2025
- Lead sponsor
- Nicox Ophthalmics, Inc.
- Diseases
- Glaucoma
- NCT number
- NCT05938699
What you commit to
- Study type: Interventional · Phase 2/3
- Participants enrolled: 18
- From 12 Dec 2023 to the primary completion date, 17 Mar 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Clinically significant ocular disease in either eye
- Uncontrolled systemic disease
- Serious hypersensitivity to topical anesthetic eye drops
- Subjects with a known hypersensitivity or contraindications to any of the ingredients in the study medications
Other
- Narrow anterior chamber angles or disqualifying central corneal thickness in either eye
Who the study is looking for
- ≥18 years of age
- Either gender
- Subjects without glaucoma
- Qualifying IOP at Screening Visit
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mayo Clinic Coordinator of this site? Confirm its status | Rochester | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.