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NCT05939791Completed

Physical Exercise and Dairy Probiotics in Childhood Cancer Survivors

The Effect of Physical Exercise and Dairy Probiotics (Lactobacillus Casei) on Gut Microbiome in Childhood Cancer Survivors

Source: ClinicalTrials.gov · Last updated 16 Jan 2024

Brief summary (registry, in English)

The goal of this clinical trial is to to compare the structure of the intestinal microbiome between children shortly after treatment for acute lymphoblastic leukemia (1-3 years after cancer treatment) and healthy controls. And then to provoke a positive shift of bacterial diversity by physical activity and probiotics in cured pediatric oncology patients with persistent gut microbiome disruptions. The main question\[s\] it aims to answer are: * Are differences in bacterial richness between healthy controls and pediatric oncology patients ≥12 months after cancer treatment apparent? * Has the combination of physical exercise and probiotics had a positive influence on the structure of the gut microbiome in childhood cancer survivors in remission? Two times per week of physical activity and daily dairy consumption with probiotics will be required of participants for eight weeks.

Status (registry)
Completed
Study type
Interventional
Enrollment
29 (actual)
First submitted
3 Jul 2023
Start date
1 Apr 2022
Primary completion date
31 Dec 2023
Lead sponsor
Comenius University
NCT number
NCT05939791

What you commit to

  • Study type: Interventional
  • Participants enrolled: 29
  • From 1 Apr 2022 to the primary completion date, 31 Dec 2023
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • acute respiratory infection during intervention

Other

  • more than 20% skipped exercise training sessions

Who the study is looking for

  • \- children previously diagnosed and treated for acute lymphoblastic leukemia in remission between 1 and 3 years

Age in the registry: 6 years to 12 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Department of Pediatric Hematology National Institute of Children's Diseases Bratislava
Coordinator of this site? Confirm its status
BratislavaSlovakiaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.