NCT05940285Active, not recruiting
Evaluation of the Diagnostic Performance of Dynamic Myocardial Perfusion Scintigraphy in Comparison With Invasive Intracoronary FFR Measurement, in the Assessment of Significant Residual Coronary Stenosis After Acute Coronary Syndrome: Dyna-MI Pilot Study.
Source: ClinicalTrials.gov · Last updated 8 Apr 2026
Brief summary (registry, in English)
Dynamic 99mTc-Tetrofosmin CZT-SPECT myocardial perfusion imaging (MPI) is an advanced functional imaging technique giving important myocardial flow quantification added data in comparison with conventional MPI, especially in coronary multi vessel disease. A large-scale validation of diagnostic performances of myocardial flow reserve (MFR) estimated with Dynamic 99mTc-Tetrofosmin CZT-SPECT MPI would allow a non-invasive approach instead of invasive intra-coronary fractional flow reserve (FFR) measurement. The aim of this prospective study is to assess diagnostic performances of MFR calculated with dynamic 99mTc-Tetrofosmin CZT-SPECT MPI in comparison with invasive intra-coronary FFR measurement in patients with significant residual coronary arteries stenosis after acute coronary syndrome .
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 3 Jul 2023
- Start date
- 20 Oct 2023
- Primary completion date
- 20 May 2026
- Lead sponsor
- Nantes University Hospital
- Diseases
- Coronary artery disease
- NCT number
- NCT05940285
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 20 Oct 2023 to the primary completion date, 20 May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Medical history of myocardial infarction or coronary artery bypass surgery.
Age
- Reproductive age women.
Other
- Non adult patient.
- Adult patient under tutelage.
- Cardiogenic shock.
- Cardiomyopathy.
- Regadenoson/adenosine/FFR contraindication.
- 99mTc-Tetrofosmin hypersensibility.
- Small non-culprit coronary arteries.
- Participation to another interventional study.
Who the study is looking for
- Adult patient.
- Multi vessel coronary arteries disease (at least one non-culprit coronary stenosis \>= 50%) diagnosis during
- primary percutaneous coronary intervention \< 12h after ST-elevation myocardial infarction opercutaneous revascularisation of the culprit lesion within 24 to 48 hours of an acute non-ST-segment elevation coronary syndrome.
- Written consent.
- Social security affiliation
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Nantes University Hospital Coordinator of this site? Confirm its status | Nantes | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.