NCT05943626Recruiting
Circadian Intervention to Improve Cardiometabolic Health
Timing of Circadian Synchronizers: The TOCS Study
Source: ClinicalTrials.gov · Last updated 5 Aug 2026
Brief summary (registry, in English)
The overall goal is to examine the efficacy of a circadian intervention in people with overweight and obesity and habitual short sleep duration (HSSD). Participants will undergo a randomized controlled trial, with circadian intervention and control (healthy lifestyle) groups. The circadian intervention is designed to reduce nighttime light exposure and after-dinner snack food intake. Alternatively, the control group will receive basic health information (e.g., physical activity, goal setting, and nutrition when eating out).
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 12 Jun 2023
- Start date
- 13 Jun 2023
- Primary completion date
- Dec 2026
- Lead sponsor
- University of Utah
- Diseases
- Obesity, Type 2 diabetes
- NCT number
- NCT05943626
What you commit to
- Study type: Interventional
- Planned participants: 20
- From 13 Jun 2023 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Weight change: \>10% of body weight over prior six months
Other illness
- Clinically diagnosed sleep disorder or major psychiatric illness
- Evidence of significant organ dysfunction or disease (e.g., diagnosed diabetes, cardiovascular disease, or kidney disease)
- Shift-work: current or history of within last year
- Current enrollment in weight loss or physical activity program like the Diabetes Prevention Program
Lab values
- Use of prescription drugs or substances known to influence sleep or glucose metabolism
Other
- Experiencing menopause or post-menopausal
- Currently pregnant or planning to become pregnant, or currently lactating.
- Currently smoking
- Alcohol intake \>3 drinks per day or \>14 drinks per week
Who the study is looking for
- Age: 18-45 years old; equal numbers of men and women
- Body mass index (BMI): 25.0-34.9 kg/m2,
- Sleep Habits: habitual self-reported average total sleep time (TST) \<6.5 hours per night for prior 6 months
Age in the registry: 18 years to 45 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| College of Health Research Complex--University of Utah Coordinator of this site? Confirm its status | Salt Lake City | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.