NCT05948956Completed
Effects of Exercise Training and Ketone Ester on Muscle Strength and Cardiovascular Response in Parkinson's Disease
Effects of Combined Exercise Training and Ketone Ester on Muscle Strength and Cardiovascular Response in Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 28 Apr 2026
Brief summary (registry, in English)
The main purpose of this study is to assess changes in exercise capacity in people with Parkinson's disease before and after an exercise training program with ketone ester supplementation.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 19 (actual)
- First submitted
- 26 Jun 2023
- Start date
- 28 Jul 2023
- Primary completion date
- 21 Mar 2025
- Lead sponsor
- University of Michigan
- Diseases
- Parkinson disease
- NCT number
- NCT05948956
What you commit to
- Study type: Interventional
- Participants enrolled: 19
- From 28 Jul 2023 to the primary completion date, 21 Mar 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Any contraindications to MRI (metal implants, severe claustrophobia, inability to lie still for 1 hour, etc.)
Other illness
- Any recent changes in EKG, history of myocardial infarction or other cardiac event or other cardiac contraindications to exercise
- History of symptoms in exercise that preclude safe and comfortable participation, such as dizziness and lightheadedness, orthostasis, severe symptomatic leg or back musculoskeletal pain, painful neuropathy, significant ankle edema or medication side effects
- History of symptomatic cardiovascular or pulmonary disease interfering with exercise
- History of active rheumatoid arthritis
- History of uncontrolled chronic pain syndrome
- Any other history of medical or psychiatric comorbidity precluding safe participation in the project
- Poorly controlled diabetes
- Clinically significant dementia
Other
- Inability to use a step, stand, walk, or use a stationary cycle ergometer
- Pregnancy or breastfeeding
Who the study is looking for
- Diagnosis of Parkinson's Disease
Age in the registry: 45 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Domino's Farms Coordinator of this site? Confirm its status | Ann Arbor | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.