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NCT05950867Recruiting

Prevalence of Wild-type TTR Cardiac Amyloidosis in Patients With Polyneuropathy of Unknown Cause.

Prevalence of Wild-type TTR Cardiac Amyloidosis in Patients With Polyneuropathy of Unknown Cause: a Prospective Monocentric Study (CAP-TTR)

Source: ClinicalTrials.gov · Last updated 22 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

To investigate to what extent chronic axonal length-dependent polyneuropathy (CAP) and/or small-fiber neuropathy (SFN) is part of early non-cardiac manifestations of wild-type TTR cardiac amyloidosis (wtTTR-CA). Consequently, explore whether this could ultimately lead to faster diagnosis and clinical outcome of wild-type TTR cardiac amyloidosis (wtTTR-CA).

Status (registry)
Recruiting
Study type
Interventional
Enrollment
150 (estimated)
First submitted
21 Apr 2023
Start date
28 Jul 2023
Primary completion date
1 Jun 2026
Lead sponsor
Universitair Ziekenhuis Brussel
Diseases
Amyloidosis
NCT number
NCT05950867

What you commit to

  • Study type: Interventional
  • Planned participants: 150
  • From 28 Jul 2023 to the primary completion date, 1 Jun 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Age

  • Patients younger than 60 years

Other

  • Known cause of polyneuropathy
  • Other types of peripheral neuropathy than chronic axonal length-dependent polyneuropathy (CAP) and/or small-fiber neuropathy (SFN).

Who the study is looking for

  • Patients with chronic axonal length-dependent polyneuropathy (CAP) and/or small-fiber neuropathy (SFN) without well-defined etiology.
  • Age: \>= 60 years
  • Male and female gender
  • Written informed consent

Age in the registry: 60 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
UZ Brussel
Coordinator of this site? Confirm its status
JetteBelgiumRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.