NCT05957146Completed
Kinetics of Extracellular Vesicles in Hemodialysis
Source: ClinicalTrials.gov · Last updated 3 Oct 2024
Brief summary (registry, in English)
The aim of this observational study is to gain insight into the kinetics of extracellular vesicles (EVs), derived from both in- (i.e. bio-incompatibility) and outside (tissue-injury) the extracorporeal circuit (ECC), during standard hemodialysis (HD) in adult prevalent end-stage kidney disease (ESKD) patients treated with HD. During a single HD session, blood samples for EV-assessment will be taken at several time points and at different sampling sites in the extracorporeal circuit (sampling point 1: before the rollerpump, arterial line; sampling point 2: after the rollerpump and before the dialyzer, sampling point 3: after the dialyzer, efferent line).
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 6 (actual)
- First submitted
- 4 Jul 2023
- Start date
- 7 Nov 2023
- Primary completion date
- 9 Feb 2024
- Lead sponsor
- Amsterdam UMC, location VUmc
- Diseases
- Chronic kidney disease
- NCT number
- NCT05957146
What you commit to
- Study type: Observational
- Participants enrolled: 6
- From 7 Nov 2023 to the primary completion date, 9 Feb 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Active infection, malignancy, auto-immune disease, or treatment with immunosuppressive medication.
Other illness
- Allergy to polysulfone dialysers
- Life expectancy \<3 months due to non-renal disease
Other
- Access recirculation
Who the study is looking for
- Age \>18 years
- Stable clinical situation: free of infection, no recent admission
- HD \>3 months
- Haemoglobin level \>6,2 mmol/L
- Residual diuresis \<200mL/24h
- Willing and able to give written informed consent.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Dianet Amsterdam Coordinator of this site? Confirm its status | Amsterdam | Netherlands | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.