NCT05962034CompletedPhase 4
Thromboxane Function in Women With Endometriosis
The Role of Thomboxane A2 and it's Receptor in Vascular Regulation in Women With Endometriosis
Source: ClinicalTrials.gov · Last updated 27 Jul 2026
Brief summary (registry, in English)
The goal of this clinical trial is to compare neurovascular regulation in women with endometriosis and healthy women. The main questions it aims to answer are: * Do women with endometriosis have greater blood pressure and pain responses to a stimulus than healthy women? * Do women with endometriosis have greater platelet activity than healthy women? Participants will take aspirin and/or placebo and will: * perform hand grip exercise and cold pressor tests * undergo iontophoresis and blood draw Researchers will compare women with and without endometriosis to see if there is a difference in neurovascular regulation.
- Status (registry)
- Completed
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 21 (actual)
- First submitted
- 30 Jun 2023
- Start date
- 1 Jan 2024
- Primary completion date
- 1 Jul 2026
- Lead sponsor
- Penn State University
- Diseases
- Endometriosis
- NCT number
- NCT05962034
What you commit to
- Study type: Interventional · Phase 4
- Participants enrolled: 21
- From 1 Jan 2024 to the primary completion date, 1 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Currently using hormone replacement therapy (or have used within previous 6 months)
- Any current medications which could conceivably alter cardiovascular responses (e.g. antihypertension medication, diuretic, digoxin)
- Allergy or hypersensitivity to investigational agents
Other illness
- Diagnosed cardiovascular disease
- Known skin allergies or current rash, skin disease, disorders of pigmentation
- Diabetes
- Renal disease, renal artery stenosis, renal impairment
- Liver disease
- Stage II Hypertension (blood pressure \>140/\>90 mmHg)
- Raynaud's syndrome
Other
- Currently pregnant or breastfeeding
- BMI over 35
- Nicotine use (e.g., smoking, chewing tobacco, vaping, etc.)
- Hypotension (blood pressure \< 90/60 mmHg)
- Immunosuppressed/immunocompromised
Who the study is looking for
- Born with a uterus
- 18-45 years old
- With and without endometriosis
Age in the registry: 18 years to 45 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Noll Laboratory Coordinator of this site? Confirm its status | University Park | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.