NCT05967091Active, not recruiting
Ryme Medical TLD Pilot Study
Targeted Lung Denervation (TLD) With the Ryme Medical Lung Denervation System in Patients With Chronic Obstructive Pulmonary Disease (COPD) - Ryme Medical TLD Pilot Study
Source: ClinicalTrials.gov · Last updated 13 Aug 2025
Brief summary (registry, in English)
Targeted lung denervation (TLD) with the Ryme Medical Lung Denervation System in patients with chronic obstructive pulmonary disease (COPD) - Ryme Medical TLD Pilot Study
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 14 Jul 2023
- Start date
- 6 Mar 2024
- Primary completion date
- 22 May 2025
- Lead sponsor
- Ryme Medical, Inc.
- Diseases
- COPD
- NCT number
- NCT05967091
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 6 Mar 2024 to the primary completion date, 22 May 2025
- 7 sites in 6 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior lung intervention with device in place
- Current chemotherapy or radiation therapy and/or has received treatment within 6 months
Other illness
- Recent COPD exacerbation or respiratory infection
- Pulmonary nodule or malignancy requiring treatment
- Clinically significant serious or unstable medical conditions (e.g., heart disease requiring treatment, uncontrolled diabetes)
Other
- Current smoker, using e-cigarettes or vaping, or taking any inhaled substances not prescribed by a physician
- Pregnant, nursing, or intent to become pregnant during study duration
Who the study is looking for
- Symptomatic chronic obstructive pulmonary disease
- ≥40 years of age
- Smoking history of at least 10 pack years
- Candidate for bronchoscopy in the opinion of the Investigator
Age in the registry: 40 years to - · Sex: All · Does not accept healthy volunteers
Sites (7)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Karl Landsteiner Institute for Lung Research Coordinator of this site? Confirm its status | Vienna | Austria | Unknown status |
| Melbourne Health - The Royal Melbourne Hospital Coordinator of this site? Confirm its status | Melbourne | Australia | Unknown status |
| Macquarie University Coordinator of this site? Confirm its status | Sydney | Australia | Unknown status |
| Rigshospitalet Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
| Royal Brompton Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
| Healthycore Coordinator of this site? Confirm its status | Tbilisi | Georgia | Unknown status |
| University of Groningen Medical Center Coordinator of this site? Confirm its status | Groningen | Netherlands | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.