NCT05977699CompletedPhase 4
Reversibility of Methacholine Induced Bronchoconstriction
Salbutamol Reversal of Methacholine Induced Bronchoconstriction: Vibrating Mesh Nebulizer Versus Pressurized Metered Dose Inhaler
Source: ClinicalTrials.gov · Last updated 4 May 2026
Brief summary (registry, in English)
The study will compare salbutamol reversibility of methacholine induced bronchoconstriction between a pressurized metered dose inhaler with a spacer versus nebulizer administration using a vibrating mesh nebulizer.
- Status (registry)
- Completed
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 16 (actual)
- First submitted
- 19 Jun 2023
- Start date
- 12 Jan 2024
- Primary completion date
- 25 Nov 2024
- Lead sponsor
- University of Saskatchewan
- Diseases
- Asthma
- NCT number
- NCT05977699
What you commit to
- Study type: Interventional · Phase 4
- Participants enrolled: 16
- From 12 Jan 2024 to the primary completion date, 25 Nov 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- respiratory infection within 4 weeks of Visit 1
Other
- exposure to triggers of respiratory symptoms within 4 weeks of Visit 1
- currently pregnant or breastfeeding
- current smoker (cigarettes, vaping)
Who the study is looking for
- age (years) at least 18, male or female
- no confounding health issue (i.e. no health conditions, other than asthma, that would put the participant at risk or affect data integrity)
- baseline FEV1 ≥ 65% predicted (per Quanjer GLI 2012)
- methacholine PD20 ≤ 800mcg
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Asthma Research Lab University of Saskatchewan Room 346 Ellis Hall Coordinator of this site? Confirm its status | Saskatoon | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.