NCT05977712Recruiting
Circadian Rhythm and Other Factors in Memory Clinic Patients
Circadian Rhythm and Other Individual Factors Among Memory Clinic Patients
Source: ClinicalTrials.gov · Last updated 19 Feb 2026
Brief summary (registry, in English)
The CIRCAME study is a bicentric study of patients from 2 memory clinics in Paris. The main objective is to identify circadian rhythm components and other individual risk factors (sociodemographic, behavioral, and health related factors) associated with the diagnosis of subtypes (AD, Lewy bodies, vascular, frontotemporal dementia) and stages (cognitively healthy, mild cognitive impairment, clinical dementia) of dementia, independent of known risk factors (sociodemographic and genetic) and assess the relevance of use of these factors in primary care for screen of dementia including subtypes and stages. A secondary objective is to determine factors associated with progression of the disease, in terms of cognitive decline and limitations in activities of daily living, as well as progression to dementia among cognitively healthy controls and patients with mild cognitive impairment, up to 15 years after the inclusion period.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 1200 (estimated)
- First submitted
- 28 Jul 2023
- Start date
- 6 Mar 2024
- Primary completion date
- Mar 2027
- Lead sponsor
- Assistance Publique - Hôpitaux de Paris
- Diseases
- Lewy body dementia, Alzheimer disease
- NCT number
- NCT05977712
What you commit to
- Study type: Observational
- Planned participants: 1200
- From 6 Mar 2024 to the primary completion date, Mar 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Skin allergy to plastic
- Diagnosis of psychiatric disorder that can explain all cognitive symptoms
Other
- Inability to come accompanied for patients with a Mini-Mental State Examination (MMSE) cognitive score ≤18 or a clinician assessment indicating the need to be accompanied (e.g. wheelchair use, agitation)
- Participation at the time of inclusion and during the 9-day period of wearing the accelerometer in interventional research with potential impact on circadian rhythm
Who the study is looking for
- Patient of legal age (18 or over)
- Signed informed consent form
- Patient affiliated to the french social security system
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hôpital de Jour Gériatrique et consultation mémoire Coordinator of this site? Confirm its status | Paris | France | Recruiting |
| Centre de neurologie Cognitive / CMRR Coordinator of this site? Confirm its status | Paris | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.