NCT05979337Completed
Brief Interventions in Chronic Migraine
Brief Behavioral Interventions for Adults With Chronic Migraine
Source: ClinicalTrials.gov · Last updated 28 Aug 2026
Brief summary (registry, in English)
People with chronic migraine headaches face many challenges, including high levels of daily pain, disturbances to everyday activities and sleep, and problems with mood such as depression or anxiety. This trial is being completed to study whether changing an individual's behaviors may have an impact as a treatment for migraine headaches. Eligible participants will be randomized to one of the four arms. This study will be conducted remotely without in-person contact. Study Hypothesis: * There is a main effect of attending either the Empowered Relief and Health Education intervention on reductions in migraine-related disability 1 month after completing either intervention * There is a main effect of Empowered Relief and Health Education interventions on reducing pain-related catastrophizing and migraine symptom severity 1 month after completing either intervention (secondary hypothesis) * The expected reductions in migraine-related disability, pain catastrophizing, and migraine symptom severity will be maintained at secondary time points (2 months, 3 months, and 6 months after completing either intervention) (secondary hypothesis)
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 180 (actual)
- First submitted
- 28 Jul 2023
- Start date
- 11 Oct 2023
- Primary completion date
- 4 Mar 2026
- Lead sponsor
- University of Michigan
- Diseases
- Migraine
- NCT number
- NCT05979337
What you commit to
- Study type: Interventional
- Participants enrolled: 180
- From 11 Oct 2023 to the primary completion date, 4 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Currently receiving cognitive-behavioral therapy for pain or migraine
Other illness
- Open litigation regarding a medical condition, as assessed in preliminary study screening
- Inability to provide informed consent and complete study procedures (e.g., indications of suspected major cognitive impairment via observations of study staff during consenting) that would preclude comprehension or participation in study protocols
- Failure to complete at least 7 out of 14 pre-intervention daily diaries
Who the study is looking for
- Self-reported neurologist diagnosis of chronic migraine
- Meets diagnostic criteria for chronic migraine according to the Identify Chronic Migraine (IDCM) self-reported instrument
- English-speaking
- Internet access and audio-visual conferencing capability (e.g., Zoom meetings by phone or computer) in the home
- Age 18 years or older
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Michigan Coordinator of this site? Confirm its status | Ann Arbor | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.