NCT05980520Completed
Study on the Treatment of Taurine in Children With Autism
Taurine Supplementation Improves Core Symptoms in Children With Autism Spectrum Disorders: an Exploratory Randomized, Double-blinded, Controlled Trial
Source: ClinicalTrials.gov · Last updated 6 Apr 2025
Brief summary (registry, in English)
In the treatment of autism spectrum disorders (ASD), medication is only an adjunct, and the main treatment modalities are education and behavioral therapy. People with autism incur huge medical and educational costs, which puts a great financial burden on families.Taurine is one of the abundant amino acids in tissues and organs, and plays a variety of physiological and pharmacological functions in nervous, cardiovascular, renal, endocrine and immune systems. A large number of studies have shown that taurine can improve cognitive function impairment under various physiological or pathological conditions through a variety of mechanisms, taurine can increase the abundance of beneficial bacteria in the intestine, inhibit the growth of harmful bacteria, and have a positive effect on intestinal homeostasis. This study intends to analyze the effect of taurine supplementation on ASD, and explore the possible mechanism by detecting intestinal symptoms, intestinal flora, markers of oxidative stress and clinical symptoms of ASD.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 64 (actual)
- First submitted
- 31 Jul 2023
- Start date
- 18 Aug 2023
- Primary completion date
- 20 Jun 2024
- Lead sponsor
- Guizhou Provincial People's Hospital
- Diseases
- Autism
- NCT number
- NCT05980520
What you commit to
- Study type: Interventional
- Participants enrolled: 64
- From 18 Aug 2023 to the primary completion date, 20 Jun 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Children who have taken taurine supplements or medications in the past 3 months.
Other illness
- Rett behavioral sign, cerebral palsy, other congenital diseases, associated with other inherited metabolic behavioral signs, epilepsy.
- Children who have had an acute or chronic infectious disease in the past 3 months.
- Children with abnormal liver and kidney function, chronic pulmonary heart disease.
Other
- Parents or patients refuse to participate in the study.
- The investigator determines that the subject is unable to comply with the study requirements.
Who the study is looking for
- Aged 2.5-18 years at enrollment.
- Meet the diagnosis criteria of ASD by the diagnostic and statistical manual of mental disorders(DSM-5).
Age in the registry: 30 months to 18 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Guizhou Provincial People's Hospital Coordinator of this site? Confirm its status | Guiyang | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.