NCT05982158Recruiting
Avatar-mediated Therapy Versus Cognitive Behavioural Therapy for Persisting Experiences of Hearing Voices
Remotely Delivered Avatar-mediated Therapy Versus Cognitive Behavioural Therapy for Persisting Auditory Hallucinations: Randomised Controlled Superiority Trial
Source: ClinicalTrials.gov · Last updated 22 Nov 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The aim of this study is to compare the effects of a new psychological therapy, Avatar Therapy, to the current standard therapy, Cognitive Behavioural Therapy (CBT), in improving outcomes in people living with psychotic disorders who have persisting experiences of hearing voices (auditory verbal hallucinations, AVHs).
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 212 (estimated)
- First submitted
- 20 Jul 2023
- Start date
- 8 Aug 2023
- Primary completion date
- Dec 2026
- Lead sponsor
- Swinburne University of Technology
- Diseases
- Schizophrenia
- NCT number
- NCT05982158
What you commit to
- Study type: Interventional
- Planned participants: 212
- From 8 Aug 2023 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Within the last month or planned at the time of intake: a change of antipsychotic medication,
- Current or within the past 3 months receipt of individual psychological therapy for hearing voices, or receipt of electro-convulsive therapy or other brain stimulation treatment;
Other illness
- Auditory verbal hallucinations attributable to a primary substance use disorder or organic disorder
Other
- Estimated full scale IQ \< 70 (using the Test of Premorbid Functioning, TOPF)
- AVHs in a language not spoken by the therapists.
Who the study is looking for
- Schizophrenia-related disorder or a mood disorder with psychotic symptoms diagnosis confirmed using the Structured Clinical Interview for DSM (SCID)
- Experiencing current auditory verbal hallucinations as measured by the Positive and Negative Syndrome Scale (PANSS) item P3 ≥ 4
- Auditory verbal hallucinations present for at least one year
- AVHs include significant negative content (PSYRATS item 6 ≥ 2) and/or AVHs are distressing (PSYRATS item item 9 ≥ 2)
- Current treatment with antipsychotic medication, or has been treated with antipsychotic medication in the past, with at least two different antipsychotic compounds, and these have been discontinued due to insufficient treatment response and/or poor tolerability.
- Access to the internet and a computer or other device on which videoconferencing software can be used
- Sufficient fluency in English for meaningful participation
- Age 18 or over
- Ability to give informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Swinburne University of Technology Coordinator of this site? Confirm its status | Hawthorn | Australia | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.