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NCT05982847Recruiting

National Blood Pressure Screening in Children to Improve Paediatric Healthcare in South Africa

National Blood Pressure Screening in Children to Optimise Clinical Management of Paediatric Hypertension in South Africa

Source: ClinicalTrials.gov · Last updated 7 Apr 2026

Brief summary (registry, in English)

The Childhood Hypertension Consortium of South Africa (CHCSA) was established to foster relationships between the healthcare sector and schools through community engagement and outreach as well as contributing to the decolonization of normative paediatric blood pressure reference values. To date, there has been no nation-wide project in South Africa to determine nationally representative normal blood pressure reference values, nor to estimate the true prevalence of hypertension in the paediatric population of the country. This study will provide critical information on the understanding of blood pressure and hypertension in children, especially of African ancestry. Not only will this effort contribute to the development of the first nationally representative normal reference values of blood pressure but will also benefit healthcare providers in the sector with a clear guideline on the management of high blood pressure in children as developed by experts working with these challenges daily.

Status (registry)
Recruiting
Study type
Observational
Enrollment
22464 (estimated)
First submitted
1 Aug 2023
Start date
1 Apr 2024
Primary completion date
30 Nov 2028
Lead sponsor
North-West University, South Africa
NCT number
NCT05982847

What you commit to

  • Study type: Observational
  • Planned participants: 22464
  • From 1 Apr 2024 to the primary completion date, 30 Nov 2028
  • 11 sites in 2 countries
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • randomly selected children who choose not to participate (lack of assent/consent), even if parent's permission was received,
  • Children will be excluded from the analysis for the determination of normative reference values for blood pressure and anthropometry if taking certain concomitant medication(s) that may affect their blood pressure, or any underlying disease e.g., chronic kidney disease, chronic heart disease etc. that may raise blood pressure.

Other illness

  • conditions that interfere with a patient's ability to follow study guidelines, e.g., the use of drugs, alcohol or tobacco products

Age

  • ages \>18 years or under 5 years

Other

  • circumstances interfere with the participant's ability to give informed consent (diminished understanding or comprehension, or any language barriers that may pose potential risk in participation under false expectations)

Who the study is looking for

  • All children between ages 5-\<18 years
  • All children with voluntary assent/consent and parent's permission

Age in the registry: 5 years to 18 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (11)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
University of Zurich
Coordinator of this site? Confirm its status
ZurichSwitzerlandNot yet recruiting
University of the Free State
Coordinator of this site? Confirm its status
BloemfonteinSouth AfricaRecruiting
University of Cape Town
Coordinator of this site? Confirm its status
Cape TownSouth AfricaNot yet recruiting
Red Cross War Memorial Children Hospital
Coordinator of this site? Confirm its status
Cape TownSouth AfricaNot yet recruiting
South African Medical Research Council
Coordinator of this site? Confirm its status
Cape TownSouth AfricaNot yet recruiting
University of KwaZulu-Natal
Coordinator of this site? Confirm its status
DurbanSouth AfricaNot yet recruiting
University of the Witwatersrand
Coordinator of this site? Confirm its status
JohannesburgSouth AfricaRecruiting
Walter Sisulu University
Coordinator of this site? Confirm its status
MthathaSouth AfricaNot yet recruiting
University of Limpopo
Coordinator of this site? Confirm its status
PolokwaneSouth AfricaNot yet recruiting
Nelson Mandela Metropolitan University
Coordinator of this site? Confirm its status
Port ElizabethSouth AfricaRecruiting
Hypertension in Africa Research Team (HART), North-West University
Coordinator of this site? Confirm its status
PotchefstroomSouth AfricaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.