NCT05982847Recruiting
National Blood Pressure Screening in Children to Improve Paediatric Healthcare in South Africa
National Blood Pressure Screening in Children to Optimise Clinical Management of Paediatric Hypertension in South Africa
Source: ClinicalTrials.gov · Last updated 7 Apr 2026
Brief summary (registry, in English)
The Childhood Hypertension Consortium of South Africa (CHCSA) was established to foster relationships between the healthcare sector and schools through community engagement and outreach as well as contributing to the decolonization of normative paediatric blood pressure reference values. To date, there has been no nation-wide project in South Africa to determine nationally representative normal blood pressure reference values, nor to estimate the true prevalence of hypertension in the paediatric population of the country. This study will provide critical information on the understanding of blood pressure and hypertension in children, especially of African ancestry. Not only will this effort contribute to the development of the first nationally representative normal reference values of blood pressure but will also benefit healthcare providers in the sector with a clear guideline on the management of high blood pressure in children as developed by experts working with these challenges daily.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 22464 (estimated)
- First submitted
- 1 Aug 2023
- Start date
- 1 Apr 2024
- Primary completion date
- 30 Nov 2028
- Lead sponsor
- North-West University, South Africa
- Diseases
- Obesity, High blood pressure
- NCT number
- NCT05982847
What you commit to
- Study type: Observational
- Planned participants: 22464
- From 1 Apr 2024 to the primary completion date, 30 Nov 2028
- 11 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- randomly selected children who choose not to participate (lack of assent/consent), even if parent's permission was received,
- Children will be excluded from the analysis for the determination of normative reference values for blood pressure and anthropometry if taking certain concomitant medication(s) that may affect their blood pressure, or any underlying disease e.g., chronic kidney disease, chronic heart disease etc. that may raise blood pressure.
Other illness
- conditions that interfere with a patient's ability to follow study guidelines, e.g., the use of drugs, alcohol or tobacco products
Age
- ages \>18 years or under 5 years
Other
- circumstances interfere with the participant's ability to give informed consent (diminished understanding or comprehension, or any language barriers that may pose potential risk in participation under false expectations)
Who the study is looking for
- All children between ages 5-\<18 years
- All children with voluntary assent/consent and parent's permission
Age in the registry: 5 years to 18 years · Sex: All · Accepts healthy volunteers
Sites (11)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Zurich Coordinator of this site? Confirm its status | Zurich | Switzerland | Not yet recruiting |
| University of the Free State Coordinator of this site? Confirm its status | Bloemfontein | South Africa | Recruiting |
| University of Cape Town Coordinator of this site? Confirm its status | Cape Town | South Africa | Not yet recruiting |
| Red Cross War Memorial Children Hospital Coordinator of this site? Confirm its status | Cape Town | South Africa | Not yet recruiting |
| South African Medical Research Council Coordinator of this site? Confirm its status | Cape Town | South Africa | Not yet recruiting |
| University of KwaZulu-Natal Coordinator of this site? Confirm its status | Durban | South Africa | Not yet recruiting |
| University of the Witwatersrand Coordinator of this site? Confirm its status | Johannesburg | South Africa | Recruiting |
| Walter Sisulu University Coordinator of this site? Confirm its status | Mthatha | South Africa | Not yet recruiting |
| University of Limpopo Coordinator of this site? Confirm its status | Polokwane | South Africa | Not yet recruiting |
| Nelson Mandela Metropolitan University Coordinator of this site? Confirm its status | Port Elizabeth | South Africa | Recruiting |
| Hypertension in Africa Research Team (HART), North-West University Coordinator of this site? Confirm its status | Potchefstroom | South Africa | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.