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NCT05983185Recruiting

Prism Adaptation Therapy (PAT) for Right Brain Stroke Rehabilitation

Prism Adaptation Treatment (PAT) for Right Brain Stroke Rehabilitation

Source: ClinicalTrials.gov · Last updated 23 Apr 2026

Brief summary (registry, in English)

After a right brain stroke, \>50% of Veterans experience problems with dressing, eating, self-care or steering their wheelchairs because their ability to move, orient, and respond toward the left side is limited: spatial neglect. Spatial neglect prevents them from functioning independently, and their needs in the hospital and at home are greatly increased. An effective treatment for spatial neglect is 10 days of visuomotor training while wearing optical prisms (PAT), however many clinicians \[fail to diagnose spatial neglect and use this approach. In this study, the investigators will develop a brain scanning test that could objectively identify the Veterans with spatial neglect after stroke who are the best candidates to receive PAT and recover their ability to function. When the research is complete, the investigators expect that brain scans done in the hospital can guide the team to refer Veterans to PAT rehabilitation: improving daily life function\] and quality of life.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
244 (estimated)
First submitted
14 Jul 2023
Start date
1 Feb 2023
Primary completion date
31 Dec 2026
Lead sponsor
VA Office of Research and Development
Diseases
Stroke
NCT number
NCT05983185

What you commit to

  • Study type: Interventional
  • Planned participants: 244
  • From 1 Feb 2023 to the primary completion date, 31 Dec 2026
  • 4 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Has had a clinical left brain stroke or has neuroimaging evidence of prior stroke(s) including the presence of more than two lacunes with diameter greater than 15 mm.

Other illness

  • Has been diagnosed with other chronic, disabling neurological disorder (e.g. multiple sclerosis, Alzheimer Disease)

Other

  • Cannot sit up to be tested and receive PAT
  • Has \<20/50 vision when viewing with both eyes

Who the study is looking for

  • Has had a first right brain stroke \>18 years of age
  • 1-4 months post-diagnosis of right brain stroke
  • Can sit up, see out of both eyes and point to objects (\>20/50 vision in both eyes)
  • Can give informed consent to participate

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (4)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Louis Stokes VA Medical Center, Cleveland, OH
Coordinator of this site? Confirm its status
ClevelandUnited StatesRecruiting
Atlanta VA Medical and Rehab Center, Decatur, GA
Coordinator of this site? Confirm its status
DecaturUnited StatesRecruiting
VA Central Western Massachusetts Healthcare System, Leeds, MA
Coordinator of this site? Confirm its status
LeedsUnited StatesRecruiting
VA Connecticut Healthcare System West Haven Campus, West Haven, CT
Coordinator of this site? Confirm its status
West HavenUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.