NCT05987189Active, not recruiting
Diagnostic Performance of Small RNA Blood Test in Patients Undergoing Follow-up Imaging After Positive Low Dose CT Screening for Cancer of the Lung
Diagnostic Performance of Small RNA Blood Test in Patients Undergoing Follow-up Imaging After Positive Low Dose CT Screening for Cancer of the Lung "Early Detection of Lung Cancer Based on Small RNA Signatures - Boston II"
Source: ClinicalTrials.gov · Last updated 30 Sept 2026
Brief summary (registry, in English)
2,000 individuals, aged 50-80 who have received a lung-RADS category 3 or 4 result on a LDCT screening study and who are scheduled for follow-up diagnostic imaging study, biopsy, clinical consultation or surgical appointment at one of the participating hospitals.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 2000 (estimated)
- First submitted
- 26 Apr 2023
- Start date
- 18 Oct 2023
- Primary completion date
- May 2027
- Lead sponsor
- Hummingbird Diagnostics
- Diseases
- Lung cancer
- NCT number
- NCT05987189
What you commit to
- Study type: Observational
- Planned participants: 2000
- From 18 Oct 2023 to the primary completion date, May 2027
- 11 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior history of diagnosed lung cancer
- Immunosuppressive medication
Other illness
- History of gastrointestinal, hematological, breast, thyroid, and genitourinary cancer within the past 10 years
- Active infectious diseases, such blood borne viral diseases (e.g. AIDS, hepatitis)
Other
- Deemed not able to participate in the study by the investigator
Who the study is looking for
- Adult male and female patients, aged 50 to 80 years
- Received a lung RADS category 3 or 4 finding on a LDCT screening exam (first or subsequent) and are referred to undergo further diagnostic procedures for the detection of lung cancer
- Has undergone LD-CT screening exam within last 90 days and allows for blood sampling within this period
- Subject may not have undergone any invasive diagnostic procedure in relation to the suspicious nodule
- Able and willing to provide informed consent
Age in the registry: 50 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (11)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Northside Hospital Coordinator of this site? Confirm its status | Atlanta | United States | Unknown status |
| Our Lady of the Lake Regional Medical Center Coordinator of this site? Confirm its status | Baton Rouge | United States | Unknown status |
| Baptist Hospitals of Southeast Texas Coordinator of this site? Confirm its status | Beaumont | United States | Unknown status |
| Mass General Hospital Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
| Brigham and Women's Hospital Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
| Henry Ford Health Coordinator of this site? Confirm its status | Detroit | United States | Unknown status |
| Clinical Research Associates of Central PA Coordinator of this site? Confirm its status | DuBois | United States | Unknown status |
| New York Health + Elmhurst Hospitals Coordinator of this site? Confirm its status | Queens | United States | Unknown status |
| University Of Utah Health Coordinator of this site? Confirm its status | Salt Lake City | United States | Unknown status |
| Jacobi Medical Center Coordinator of this site? Confirm its status | The Bronx | United States | Unknown status |
| UMass Chan Medical School/UMass Memorial Health Coordinator of this site? Confirm its status | Worcester | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.