NCT05987527Active, not recruiting
Long-Term Follow-Up of TX200-TR101 (STEADFAST Long Term)
Long-Term Follow-Up of Patients Who Have Received an Autologous Antigen-Specific Chimeric Antigen Receptor T Regulatory Cell Therapy (CAR- Treg Therapy, TX200-TR101) in a Prior Clinical Study
Source: ClinicalTrials.gov · Last updated 4 Dec 2025
Brief summary (registry, in English)
This long-term follow-up study is being conducted to collect long-term (up to 15 years post-infusion) safety and tolerability data from subjects enrolled in studies evaluating TX200-TR101.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 11 (estimated)
- First submitted
- 30 Jun 2023
- Start date
- 15 Aug 2023
- Primary completion date
- 11 Jun 2039
- Lead sponsor
- Sangamo Therapeutics
- Diseases
- Chronic kidney disease
- NCT number
- NCT05987527
- EudraCT number
- 2022-002440-40
What you commit to
- Study type: Observational
- Planned participants: 11
- From 15 Aug 2023 to the primary completion date, 11 Jun 2039
- 5 sites in 3 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- N/A
Who the study is looking for
- Subjects who enrolled in the Phase I/IIa study TX200-KT02, received a transplanted kidney and have either completed or withdrawn from that study.
- Willing and able to provide written informed consent (IC) in accordance with local regulations and governing Independent Ethics Committee (IEC)/Institutional Review Board (IRB) requirements prior to any procedure or evaluation performed specifically for the sole purpose of the study.
Age in the registry: 18 years to 72 years · Sex: All · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospitals Leuven Coordinator of this site? Confirm its status | Leuven | Belgium | Unknown status |
| Oxford University Hospitals NHS Foundation Trust Coordinator of this site? Confirm its status | Oxford | United Kingdom | Unknown status |
| University Medical Center Groningen Coordinator of this site? Confirm its status | Groningen | Netherlands | Unknown status |
| Leiden University Medical Centre Coordinator of this site? Confirm its status | Leiden | Netherlands | Unknown status |
| Erasmus MC University Medical Center Coordinator of this site? Confirm its status | Rotterdam | Netherlands | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.