NCT05990244Recruiting
Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion
Comprehensive Assessment of Tumor Stiffness and Adhesion in Glioma Using Magnetic Resonance Elastography: A Prospective Study
Source: ClinicalTrials.gov · Last updated 2 Dec 2025
Brief summary (registry, in English)
this study will investigate the relationship between tumor stiffness and adhesion in gliomas using MRE. By utilizing preoperative MRE and Intraoperative neuronavigation, followed by comprehensive molecular pathology analysis, we aim to explore the correlation of tumor stiffness and adhesion with molecular and genetic characteristics of gliomas. Additionally, the predictive value of MRE in terms of pathological staging and prognosis will be determined. This research may pave the way for improved clinical decision-making, personalized treatment approaches, and more accurate clinical trials for glioma patients.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 6 Aug 2023
- Start date
- 1 Jan 2017
- Primary completion date
- 1 Jul 2026
- Lead sponsor
- Shengjing Hospital
- Diseases
- Glioblastoma
- NCT number
- NCT05990244
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 1 Jan 2017 to the primary completion date, 1 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- previous treatment for glioma
Other illness
- failure to proceed with surgery after MRE
Other
- inability to complete MRE due to intolerance (e.g., vibration-related discomfort or claustrophobia)
- completed MRE with suboptimal wave image quality (e.g., motion artifacts or inad-equate wave amplitude)
- missing IDH results
Who the study is looking for
- age older than 18 years
- Karnofsky performance status higher than 60
- with written informed consent
- MRE performed within one week before surgery
- tumor diameter \> 2 cm
Age in the registry: 18 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Shengjing Hospital Coordinator of this site? Confirm its status | Shenyang | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.