NCT05993091Recruiting
Mirror Therapy and Augmented Reality in Stroke Rehabilitation
Outcomes of Mirror Therapy Preceding Augmented Reality in Stroke Rehabilitation
Source: ClinicalTrials.gov · Last updated 5 Feb 2026
Brief summary (registry, in English)
This research is in line with the National Health Research Institutes (NHRI) Innovative Research Grant priority to address innovative treatment strategies for neurological disorders that are in desperate need of scientific scrutiny. Stroke is one of the major medical conditions that leads to long-term disability and causes a heavy health care and financial burden. To meet multidimensional needs of patients with stroke, hybrid interventions that combine different approaches are needed due to the complexity of stroke. Our previous research funded by the NHRI has been published and translated to stroke rehabilitation, particularly in the priming and synergic effects of robotic-assisted training and/or mirror therapy (MT). To extend from our previous research, the investigators will combine MT with augmented reality (AR), an emerging adjunct therapy in stroke rehabilitation. An AR-based intervention provides an intensive, repetitive, and context-rich training program, leading to an interesting environment with real-time feedback to increase motivation and participation.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 75 (estimated)
- First submitted
- 6 Aug 2023
- Start date
- 5 May 2023
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- National Taiwan University Hospital
- Diseases
- Stroke
- NCT number
- NCT05993091
What you commit to
- Study type: Interventional
- Planned participants: 75
- From 5 May 2023 to the primary completion date, 31 Dec 2026
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- serious medical problems or poor physical conditions that might be detrimental to study participation.
Other
- acute inflammation
Who the study is looking for
- a first-ever unilateral stroke ≥3 months and ≤3 years
- age between 30 and 80 years (Kwakkel et al., 1999)
- baseline Fugl-Meyer Assessment Upper Extremity (FMA-UE) score \>10 (Fugl-Meyer et al., 1975)
- no severe spasticity in any joints of the affected arm (modified Ashworth scale \<3) (Charalambous, 2014)
- ability to follow the instructions of the evaluator and therapists
- the ability to maintain a step-standing position for at least 30 seconds (Lloréns et al., 2015)
- ability to walk a minimum of 10 meters, with or without a device (Park et al., 2017)
- no severe vision impairments or other major neurologic diseases
- no participation in other studies during the study period
- willingness to provide informed written consent.
Age in the registry: 30 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Taipei Hospital, Ministry of Health and Welfare Coordinator of this site? Confirm its status | New Taipei City | Taiwan | Recruiting |
| Taipei Tzu Chi Hospital, Buddhist Tzu Chi Foundation Coordinator of this site? Confirm its status | New Taipei City | Taiwan | Recruiting |
| Fongyuan Hospital, Ministry of Health and Welfare Coordinator of this site? Confirm its status | Taichung | Taiwan | Recruiting |
| Wan Fang Hospital, Taipei Medical University Coordinator of this site? Confirm its status | Taipei | Taiwan | Recruiting |
| National Taiwan University Hospital Coordinator of this site? Confirm its status | Taipei | Taiwan | Recruiting |
Related publications
- Effects of mirror therapy preceding augmented reality in stroke rehabilitation: a randomized controlled trial.J Neuroeng Rehabil · 2025 · PMID 41444616
This page is information, not medical advice. Discuss any trial with your doctor.