NCT05993273Completed
Pain Control After VATS Anatomical Pulmonary Resections
Pain Control After VATS Anatomical Pulmonary Resections: Randomized Comparison Between Cryoanalgesia, Erector Spinae Plane Block and Epidural Catheter
Source: ClinicalTrials.gov · Last updated 31 Jul 2025
Brief summary (registry, in English)
In patients undergoing minimally invasive thoracoscopic surgery (video-assisted thoracoscopic surgery, or VATS), moderate to severe post-operative pain may often be experienced. The presence of pain negatively affects the perceived quality of care and can predispose to complications, as the development of chronic pain. In order to prevent post-operative pain, different multimodal pain treatment protocols are applied, consisting in combinations of local-regional anesthesiological techniques and intravenous medications. Regional anesthesia is considered essential to prevent pain in the immediate post-operative period. However, to date, there is no agreement regarding which is the most effective regional anesthesiological technique; therefore, the choice is usually based on the Anesthetist's preferences. The aim of this study is to compare three regional anesthesiological techniques (cryoanalgesia, epidural anesthesia, and erector spinae muscle plane block) routinely used during thoracoscopic lung surgery.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 75 (actual)
- First submitted
- 25 Jul 2023
- Start date
- 5 Apr 2023
- Primary completion date
- 15 Aug 2024
- Lead sponsor
- University Hospital Padova
- Diseases
- Lung cancer
- NCT number
- NCT05993273
What you commit to
- Study type: Interventional
- Participants enrolled: 75
- From 5 Apr 2023 to the primary completion date, 15 Aug 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Pre-operative use of pain medication for chronic pain or neuropathic pain
- History of previous major chest surgery
Other illness
- Allergies or contraindications to any of the treatments considered in the experimental design
Age
- Age \< 18 years
Other
- Refusal or inability to give informed consent to the study protocol
- Pregnancy
- American Society of Anesthesiologists (ASA) class \> 3
- Need for intensive care unit stay in the post-operative period
- Patients undergoing anatomical pulmonary resections different than lobectomy or segmentectomy (bi-lobectomy or pneumonectomy).
- Patients undergoing bronchial and/or vascular resections and reconstructions
Who the study is looking for
- all patients undergoing VATS anatomic pulmonary resection (lobectomy or segmentectomy) for benign or malignant disease
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Thoracic Surgery Unit Coordinator of this site? Confirm its status | Padua | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.