NCT05997875Recruiting
Transforming Hemodialysis-Related Vascular Access Education
Transforming Hemodialysis-Related Vascular Access Education (THRiVE)
Source: ClinicalTrials.gov · Last updated 25 Mar 2026
Brief summary (registry, in English)
The focus of this study is on vascular access for hemodialysis. This is a randomized clinical trial testing 3 educational approaches to help patients with advanced chronic kidney disease prepare for placement of hemodialysis vascular access. Study participants will each be assigned to one of the 3 approaches: 1) "Education", in which participants will be given a video and brochure that provide information about the types of vascular access and what can be expected before and after the vascular access is placed, 2) "Education-Plus", in which participants will be given the video and brochure and will also have sessions by telehealth with a motivational interviewing coach to provide additional support around vascular access placement, and 3) "Usual Care", in which participants will have the usual education provided by their kidney doctor and clinic staff just as if they were not in the study. Participants in all 3 groups will be asked to complete questionnaires by telephone and may be invited to be interviewed about their experience with the study intervention at the end of the study. Study participation will last for about 12 months, with most of the study activities taking place during the first 3 months.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 360 (estimated)
- First submitted
- 19 Jul 2023
- Start date
- 5 Dec 2023
- Primary completion date
- 30 Sept 2027
- Lead sponsor
- University of Pennsylvania
- Diseases
- Chronic kidney disease
- NCT number
- NCT05997875
What you commit to
- Study type: Interventional
- Planned participants: 360
- From 5 Dec 2023 to the primary completion date, 30 Sept 2027
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous placement of an AV access
- Prior appointment with surgeon for AV access evaluation or creation
Other illness
- Planning for peritoneal dialysis, preemptive transplant, or conservative management of kidney failure
- Cognitive dysfunction or severe visual impairment that prevents use of the education materials
Other
- Does not speak either English or Spanish
Who the study is looking for
- Age 18 years or older
- Nephrology visit for chronic kidney disease during the last 18 months
- Most recent eGFR less than or equal to 20 ml/min/1.73 m2 or 2-year Kidney Failure Risk Equation score greater than 40%
- Documentation in the medical record or confirmation from the treating nephrologist of a patient-nephrologist discussion about hemodialysis
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Johns Hopkins University Coordinator of this site? Confirm its status | Baltimore | United States | Recruiting |
| University of North Carolina at Chapel Hill Coordinator of this site? Confirm its status | Chapel Hill | United States | Recruiting |
| University of Pennsylvania Coordinator of this site? Confirm its status | Philadelphia | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.