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NCT06000865Recruiting

Glaucoma Rehabilitation With Action viDeo Games and Exercise - GRADE

The GRADE Randomized Trial: Glaucoma Rehabilitation With Action viDeo Games and Exercise

Source: ClinicalTrials.gov · Last updated 28 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

Falls are one of the most serious public health concerns for seniors, with significant medical and economic consequences. This concern is even higher in patients with peripheral field loss due to glaucoma because of the patients' compromised visual input. The investigators' project proposes an innovative, entertaining, easily accessible and enjoyable intervention for improving mobility and postural control function in glaucoma patients with peripheral vision loss, who are more prone to falls and suffer from fear of falling. The new intervention examined in this project can be implemented in current vision and balance rehabilitation programs, and may benefit patients with different types of visual impairment to minimize their risk of falls and improve their quality of life.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
56 (estimated)
First submitted
25 Sept 2022
Start date
9 Sept 2023
Primary completion date
30 Jul 2025
Lead sponsor
The Hong Kong Polytechnic University
Diseases
Glaucoma
NCT number
NCT06000865

What you commit to

  • Study type: Interventional
  • Planned participants: 56
  • From 9 Sept 2023 to the primary completion date, 30 Jul 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Severe medical problems (e.g., stroke, Parkinson's disease) or self-reported neurological (e.g. brain surgery, brain tumor and peripheral neuropathy), or cognitive disorders (e.g., diagnosed dementia or cognitive impairment);
  • Self-reported or medically diagnosed vestibular/ cerebellar dysfunction, history of vertigo, or severe hearing loss;
  • Using any medications for any neurological conditions or psychiatric drugs (e.g. sedative, hypnotic) that might interfere motor control; and

Age

  • Ocular diseases other than glaucoma (e.g., age-related macular degeneration, diabetic retinopathy, and moderate to severe cataract);

Other

  • Advanced glaucoma with GON of median deviation worse than -25 decibel;
  • Physical impairments (e.g. need the use of orthopedic and mobility aids) or physical limitations restricting them from independent walking;
  • Currently attending any intensive physical/balance training.

Who the study is looking for

  • Presence of moderate to severe bilateral glaucomatous optic neuropathy (GON) from primary open-angle (including normal tension) or angle-closure glaucoma, as determined by an ophthalmologist, with abnormal Glaucoma Hemifield Test on standard Humphrey Field Analyzer 24-2 testing and matching nerve-fiber layer thinning on optical coherence tomography;
  • Stable vision and visual field loss for at least 3 months;
  • With a best-corrected distance acuity of 6/12 or better (equivalent to 0.3 logMAR acuity or better to confirm that participant's central vision is preserved);
  • With a cognitive functional score of 22 or above in the Montreal Cognitive Assessment - Hong Kong version (to confirm participants' intact cognitive function).

Age in the registry: 55 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
The Hong Kong Polytechnic University
Coordinator of this site? Confirm its status
Hong KongHong Kong SAR ChinaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.