NCT06006754Completed
Influence of Enteral Microbiome on Mortality of Patients With Cardiogenic Shock
Influence of Enteral Microbiome Composition and Microbiome Dependent Metabolites on Mortality of Patients With Cardiogenic Shock
Source: ClinicalTrials.gov · Last updated 24 Aug 2025
Brief summary (registry, in English)
Cardiogenic shock is associated with a high mortality. The microbiome is a double-edged sword which can convey protective and detrimental cardiovascular effects. The significance of the enteral micobiome on cardiovascular mortality of patients with cardiogenic shock is still not known. This study aims to provide a deeper understanding of the role of the enteral microbiome and microbiome dependent metabolites in mortality and disease progression of patients with cardiogenic shock.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 40 (actual)
- First submitted
- 17 Aug 2023
- Start date
- 30 Aug 2023
- Primary completion date
- 15 Aug 2024
- Lead sponsor
- University Hospital, Essen
- Diseases
- Heart failure, Coronary artery disease
- NCT number
- NCT06006754
What you commit to
- Study type: Observational
- Participants enrolled: 40
- From 30 Aug 2023 to the primary completion date, 15 Aug 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- active chemo or radiation therapy
Other illness
- chronic inflammatory bowel disease
- short bowel syndrome
Other
- pregnancy/lactation period
- antibiotic treatment within \>24h
- artificial bowel outlet
- persistent diarrhea or vomiting in the past 3 months
- simultaneous participation in another interfering nutrition study
Who the study is looking for
- \>18y
- signs of cardiogenic shock regardless of etiology
- lactate \>3mmol/L
- and signs of organ dysfunction (urine output \<30 ml/h, cold extremities, altered mental status)
- and systolic blood pressure \<90 mmHg for \>30 minutes or need for vasopressor therapy
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital Essen Coordinator of this site? Confirm its status | Essen | Germany | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.