NCT06007404Recruiting
Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents
The Role of Circulating Meta-Inflammatory Monocytes in Adolescent Insulin Resistance
Source: ClinicalTrials.gov · Last updated 15 Oct 2026
Brief summary (registry, in English)
This research study collects health-related information and blood samples to better understand how body composition, lifestyle habits, and diet influence meta-inflammatory monocytes (MiMos) in adolescents. The hypothesis of this study is that adolescents at risk for metabolic disease have enhanced MiMo related activities leading to insulin resistance.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 175 (estimated)
- First submitted
- 10 Jun 2023
- Start date
- 6 Sept 2023
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- University of Michigan
- Diseases
- Obesity, Type 2 diabetes
- NCT number
- NCT06007404
What you commit to
- Study type: Observational
- Planned participants: 175
- From 6 Sept 2023 to the primary completion date, 31 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior diagnosis of autoimmune disease, cancer, or a cognitive or perceptual disability that would inhibit following directions of study staff
Other illness
- Allergies or intolerance to milk, soy, or palm oil
Lab values
- Use medications known to affect glucose metabolism (immunosuppressive medications, cancer medications, or high dose steroids), unless prescribed for Type 2 Diabetes management
Other
- Currently pregnant
Who the study is looking for
- Between 14 and 18 years of age
- Tanner stage 4 or 5 (mature adult stage of puberty)
- Normal weight (BMI ≥ 5th percentile \& \< 85th percentile), overweight (BMI \> 86th percentile) \& \< 94th percentile), obese weight (BMI percentile ≥ 95th percentile), and/or pre-diabetes (HbA1c \> 5.7%)
- For Type 2 Diabetes cohort, diagnosis of Type 2 Diabetes
Age in the registry: 14 years to 18 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Michigan Coordinator of this site? Confirm its status | Ann Arbor | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.