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NCT06008145Active, not recruiting

COPD Case Finding In Nottingham and District: C-FIND COPD A Pilot Study

Source: ClinicalTrials.gov · Last updated 19 Dec 2025

Brief summary (registry, in English)

The Targeted Lung Health Check (TLHC) is currently being rolled out in many regions of the United Kingdom and has just started in Nottingham. The same cohort of people are also at high risk for Chronic Obstructive Pulmonary Disease (COPD), a lung condition often caused by smoking and leading to breathlessness and cough. This study aims to provide pilot evidence of the role of breathing tests in those who have had a Computerised Tomography (CT) scan, in order to early diagnose COPD. Currently, at diagnosis, many patients have lost 30-40% of lung function already, which is not reversible. This study will use the Nottingham University Hospitals Trust Mobile Research Unit. The unit will follow the CT scanner route 2-3 weeks later, and people who have had a CT scan will be invited for breathing tests. Participants will also collect further information on potential treatment options for people diagnosed with COPD earlier -including smoking cessation, symptom management and general health advice (vaccinations, diet, activity and managing infections). There is also an optional blood test. The study aims are to determine the uptake and acceptability of breathing tests in patients at high risk of COPD, and if a community based approach co-locating with TLHC can increase uptake. A qualitative sub-study has been added to assess the opportunities or barriers for people being invited for a COPD diagnosis visit in the community. This sub-study will have a recruitment target of 20 participants. It will involve transcribed interviews. This will help determine the accessibility of the mobile research unit in use for this study.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
568 (actual)
First submitted
20 Jul 2023
Start date
21 Sept 2023
Primary completion date
31 Dec 2025
Lead sponsor
Nottingham University Hospitals NHS Trust
Diseases
COPD
NCT number
NCT06008145

What you commit to

  • Study type: Observational
  • Participants enrolled: 568
  • From 21 Sept 2023 to the primary completion date, 31 Dec 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • People currently undergoing active investigation or treatment for cancer

Other

  • Unable to provide informed consent

Who the study is looking for

  • Smoking history - either compatible with TLHC (current or ex-smoker who are high risk based on lung cancer risk scores) or if self-presenting \>10 pack years (current or ex)
  • Able to provide full informed consent.

Age in the registry: 40 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Nottingham University Hospitals NHS Trust
Coordinator of this site? Confirm its status
NottinghamUnited KingdomUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.