NCT06016348Completed
PROMISE: PRedictors Of Good outcoMes in Thrombectomy for Large Infarct Core Stroke Evaluation
Predictors of Good Outcomes in Thrombectomy for Stroke Patients Within 24 Hours From Symptom Onset With Large Infarct Core
Source: ClinicalTrials.gov · Last updated 2 Sept 2025
Brief summary (registry, in English)
Identify the factors associated with a favorable clinical outcome in participants with acute ischemic stroke and large core infarcts within 24 hours of onset who are treated with endovascular intervention.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 400 (actual)
- First submitted
- 17 Aug 2023
- Start date
- 28 Jul 2023
- Primary completion date
- 1 Aug 2025
- Lead sponsor
- 115 People's Hospital
- Diseases
- Stroke
- NCT number
- NCT06016348
What you commit to
- Study type: Observational
- Participants enrolled: 400
- From 28 Jul 2023 to the primary completion date, 1 Aug 2025
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Pre-stroke modified Rankin Score (mRS) score of \>2 (indicating previous disability)
Other illness
- Patients presenting with acute ischaemic stroke \>24 hours of stroke onset
- Intracranial hemorrhage identified by CT or MRI
- Any terminal illness such that the patient has a life expectancy of less than 1 year.
- Patients with active cancer and undergoing treatment for cancer are excluded,
Other
- Pregnancy
Who the study is looking for
- Age ≥ 18-year-old
- Patients presenting with acute ischaemic stroke within 24 hours of stroke onset
- Received mechanical thrombectomy within 24 hours of stroke onset
- Imaging criteria include:
- Large vessel occlusion on CT Angiography or MR Angiography (MRA) including tandem occlusion of the internal carotid artery and middle cerebral artery or internal carotid artery.
- Core infarct criteria:
- ASPECTS ≤5 on non-contrast CT or diffusion-weighted imaging (DWI).
- ASPECTS score \>5 and core infarct volume of 50-150 ml on CT perfusion (CTP) or reduced cerebral blood flow (rCBF) \<30% on CTP or apparent diffusion coefficient (ADC) \<620 × 10-6 mm2/s on DWI.
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Can Tho Central General Hospital Coordinator of this site? Confirm its status | Can Tho | Vietnam | Unknown status |
| Da Nang Stroke Center Coordinator of this site? Confirm its status | Da Nang | Vietnam | Unknown status |
| University Medical Center Coordinator of this site? Confirm its status | Ho Chi Minh City | Vietnam | Unknown status |
| 115 PEOPLE's HOSPITAL Coordinator of this site? Confirm its status | Ho Chi Minh City | Vietnam | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.