NCT06016465RecruitingEarly phase 1
Does Nerve Block + Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hrs?
Does Nerve Block Plus Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hours Better Than Nerve Block Alone?
Source: ClinicalTrials.gov · Last updated 6 May 2026
Brief summary (registry, in English)
For some patients who come to the emergency department for treatment of a migraine headache, peripheral headache nerve blocks (PHNB) have proven to be an efficient and effective treatment for headache relief. Previous studies have demonstrated that adding steroids as an adjunct treatment to standard migraine treatment can reduce recurrence of headaches in the subsequent few days.
- Status (registry)
- Recruiting
- Phase (registry)
- Early phase 1
- Study type
- Interventional
- Enrollment
- 84 (estimated)
- First submitted
- 21 Aug 2023
- Start date
- Sept 2023
- Primary completion date
- Dec 2027
- Lead sponsor
- Texas Tech University Health Sciences Center, El Paso
- Diseases
- Migraine
- NCT number
- NCT06016465
What you commit to
- Study type: Interventional · Early phase 1
- Planned participants: 84
- From Sept 2023 to the primary completion date, Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Chronically on steroids
Other illness
- Suspicion of secondary headache (i.e. stroke, known tumor, glaucoma)
- Headache in the setting of viral syndrome
- Known allergy to dexamethasone
- Gestational diabetes or other uncontrolled diabetes
Other
- Head trauma
- Unable to reach the patient by phone or text for follow-up
- Known to be immunocompromised
Who the study is looking for
- Meet ICHD-3 Migraine Headache Criteria
- Had a minimum 5-point reduction in headache intensity after nerve block(s) or post- block pain score of 0 to 2
- Nerve block performed with bupivacaine 0.5%
Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Medical Center of El Paso Coordinator of this site? Confirm its status | El Paso | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.