NCT06016478Completed
The Effect of 4 Weeks of L-Citrulline Supplementation on Macro- and Microvascular Function in Type 2 Diabetes
Source: ClinicalTrials.gov · Last updated 15 May 2025
Brief summary (registry, in English)
The purpose of this study is to examine the effect of 4 weeks of Citrulline supplementation on macro- and microvascular function during acute hyperglycemia in middle-aged and older adults with type 2 diabetes.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 36 (actual)
- First submitted
- 19 Aug 2023
- Start date
- 1 May 2023
- Primary completion date
- 1 Jul 2024
- Lead sponsor
- Texas Tech University
- Diseases
- Type 2 diabetes
- NCT number
- NCT06016478
What you commit to
- Study type: Interventional
- Participants enrolled: 36
- From 1 May 2023 to the primary completion date, 1 Jul 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of medications and/or any supplements that may affect outcome variables (such as arginine- or citrulline-containing supplements, nitrates, and nitroglycerin)
- Recent changes in medications within 3 months
Other illness
- Type 1 diabetes, severe cardiovascular/renal/pulmonary diseases
Age
- \< 40 years of age and \> 65 years of age
Other
- Body mass index ≥ 40 kg/m2
- Systolic blood pressure ≥ 160 mmHg
- Current smoking any tobacco use
- More than 7 alcoholic drinks/week of consumption
- Premenopausal women with an irregular menstrual cycle (oligomenorrhea) or pregnancy
Who the study is looking for
- Middle-aged and older women and men between 40-75 years old
- A physician diagnosed type 2 diabetes at least 3 months ago
- Treated with an oral hypoglycemic medication
- Body mass index \< 40 kg/m2
- Systolic blood pressure \< 160 mmHg
- Sedentary (defined as \< 120 min/week of exercise)
- Not currently participating in exercise or dietary interventions for at least 2 months prior the present study and willing to abstain from participating in those strategies during the duration of this study.
Age in the registry: 40 years to 75 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| TTU Kinesiology and Sport Management Building Coordinator of this site? Confirm its status | Lubbock | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.