NCT06016569Recruiting
Study of Early Cancer Biomarkers in Breath Condensate in Population of Individuals With High-Risk of Lung Cancer Undergoing LDCT Screening.
Prospective Validation Study of Early Cancer Biomarkers in Breath Condensate of Individuals With High-Risk of Lung Cancer Undergoing Low-Dose Computer Tomography Based Screening.
Source: ClinicalTrials.gov · Last updated 12 Feb 2026
Brief summary (registry, in English)
The trial will evaluate if the newly identified biomarkers of lung cancer in exhaled breath condensate are as a diagnostic tool comparable to the low-dose computer tomography (LDCT) implemented in lung cancer screening recently. Due to the possibility to collect breath condensate at any medical workplace and due to the relatively low financial cost of examination of the collected breath condensate could improve early diagnosis of lung cancer, differential diagnostics of lung nodules and thereby reduce both the unnecessary interventions and deaths from this type of cancer.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 3200 (estimated)
- First submitted
- 22 Aug 2023
- Start date
- 1 Jun 2023
- Primary completion date
- 31 Dec 2029
- Lead sponsor
- The Institute of Molecular and Translational Medicine, Czech Republic
- Diseases
- Lung cancer
- NCT number
- NCT06016569
What you commit to
- Study type: Interventional
- Planned participants: 3200
- From 1 Jun 2023 to the primary completion date, 31 Dec 2029
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous diagnosis of lung cancer.
Other illness
- Progressing malignant tumor on symptomatic treatment.
- Advanced dementia
- Chronic obstructive pulmonary disease or other inflammatory disease in the phase of acute exacerbation.
Who the study is looking for
- Consent to participate in a clinical trial.
- A clients within an age of 55-74 years.
- Current smoker or ex-smoker who has smoked at least 20 pack-years, provided that:
- priority will be given to clients who have smoked at least 30 pack-years.
- preference will be given to a former smoker who has not smoked for less than 15 years.
Age in the registry: 55 years to 74 years · Sex: All · Accepts healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Masaryk Memorial Cancer Institute Coordinator of this site? Confirm its status | Brno | Czechia | Recruiting |
| University Hospital Coordinator of this site? Confirm its status | Olomouc | Czechia | Not yet recruiting |
| General University Hospital in Prague Coordinator of this site? Confirm its status | Prague | Czechia | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.