NCT06016725Completed
Online Dietary and Resistance Training to Improve Physical Function in Older Cancer Survivors, E-PROOF Trial
E-PROOF: E-Intervention for Protein Intake and Resistance Training to Optimize Function
Source: ClinicalTrials.gov · Last updated 2 Jan 2026
Brief summary (registry, in English)
This phase I trial tests the feasibility, acceptability, and preliminary effectiveness of online dietary and resistance training to improve physical function in older (greater than or equal to 65-years old) cancer survivors. Declines in adequate protein and calorie intake results in faster loss of muscle mass and physical functioning in older adults. A novel approach to improving physical function in older cancer survivors (OCS) is to utilize online, tailored education and counseling from registered dietitians and exercise scientists, to improve dietary intake (protein intake, diet quality) and participation in resistance exercise. The purpose of this study is to help researchers learn whether an online dietary and resistance training intervention improves diet, exercise, physical function, and health outcomes in OCS.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 75 (actual)
- First submitted
- 26 Jun 2023
- Start date
- 28 Aug 2023
- Primary completion date
- 31 Oct 2024
- Lead sponsor
- Ohio State University Comprehensive Cancer Center
- Diseases
- Prostate cancer, Colorectal cancer
- NCT number
- NCT06016725
What you commit to
- Study type: Interventional
- Participants enrolled: 75
- From 28 Aug 2023 to the primary completion date, 31 Oct 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Currently receive cancer treatment (e.g., chemotherapy, radiation)
- Have liver and/or renal disease limiting their protein intake
Other
- Are under the care of a Registered Dietician (RD)/nutritionist
- Participating in other diet/exercise interventions
- Consume protein supplements
- Have contraindications to unsupervised exercise (e.g., walker/wheelchair use)
Who the study is looking for
- \>= 65 years of age
- A primary diagnosis of stage I-III breast, colorectal, and prostate cancer
- Completion of primary curative treatment
- Reported at least 1 physical function limitation on the RAND-36 Physical Function Subscale (PFSS) ("limited a little", "limited a lot")
- No evidence of progressive disease or second cancers
- Community-dwelling
- Able to provide consent
Age in the registry: 65 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ohio State University Comprehensive Cancer Center Coordinator of this site? Confirm its status | Columbus | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.