NCT06023784Recruiting
The Impact of LBBAP vs RVP on the Incidence of New-onset Atrial Fibrillation in Patients With Atrioventricular Block
The Impact of Left Bundle Branch Area Pacing Versus Right Ventricular Pacing on the Incidence of New-onset Atrial Fibrillation in Patients With Atrioventricular Block: a Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 21 Sept 2026
Brief summary (registry, in English)
This is a single-center, randomized controlled study. The aim of this study is to compare the impact of left bundle branch area pacing versus traditional right ventricular pacing on the incidence of atrial fibrillation in patients with atrioventricular block.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 530 (estimated)
- First submitted
- 24 Aug 2023
- Start date
- 30 Sept 2023
- Primary completion date
- 31 Dec 2028
- Lead sponsor
- Peking Union Medical College Hospital
- Diseases
- Atrial fibrillation
- NCT number
- NCT06023784
What you commit to
- Study type: Interventional
- Planned participants: 530
- From 30 Sept 2023 to the primary completion date, 31 Dec 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with the history of atrial fibrillation;
- Having difficulties in follow-up: Those who cannot accept 2-year follow-up on time due to physical condition or other reasons;
- Surgery is required within 1 year due to severe structural heart disease;
- Patients with tricuspid mechanical valve replacement, or congenital heart disease (including transposition of the great arteries, or permanent left superior vena cava, etc);
Lab values
- Baseline echocardiographic assessment of patients with impaired LV function (LVEF\<50%);
Other
- Pacemaker replacement without new implanted ventricular electrodes;
- AV block resulting from: (a) Hypertrophic cardiomyopathy(HCM), (b) ventricular septal defect repair, and those who are unlikely to achieve successful LBBAP procedure.
Who the study is looking for
- Adult patients aged 18-85;
- AV block patients with ventricular pacing indications and the expected rate of ventricular pacing(VP)\> 40%, including (a) third-degree AV block; (b) second degree AV block (type II); (c) intermittent advanced AV block with expected VP\>40%; (d) symptomatic first degree AV block and PR interval on ECG \> 300ms;
- Signed informed consent;
Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chinese Academy of Medical Sciences & Peking Union Medical College, Peking Union Medical College Hospital Coordinator of this site? Confirm its status | Beijing | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.