NCT06023953Completed
Migraine With and Without Aura Characteristics and Response to Remote Electrical Neuromodulation (REN) Treatment
Comparison of Migraine With and Without Aura in a Large Cohort: Characteristics and Response to Remote Electrical Neuromodulation (REN) Treatment
Source: ClinicalTrials.gov · Last updated 15 Aug 2025
Brief summary (registry, in English)
This is a Post-marketing, real-world evidence study investigating the safety and efficacy of the acute treatment of migraine with a Remote Electrical Neuromodulation (REN) device (Nerivio) in migraine patients with and without aura, as well as characterizing demographic and attack characteristic differences between migraine patients with and without aura. Safety will be assessed by the number and type of device-related adverse events. Efficacy will be evaluated as a change in headache pain severity from baseline to 2 hours post-treatment. Disease characteristics will look into demographic and attack differences between patients with and without aura.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 31715 (actual)
- First submitted
- 29 Aug 2023
- Start date
- 1 Jul 2023
- Primary completion date
- 30 Sept 2024
- Lead sponsor
- Theranica
- Diseases
- Migraine
- NCT number
- NCT06023953
What you commit to
- Study type: Observational
- Participants enrolled: 31715
- From 1 Jul 2023 to the primary completion date, 30 Sept 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Users who prospectively reported having aura only once
Who the study is looking for
- Users aged 8 years old and above
- Users who treated their migraine attacks with the Nerivio device at least twice
- Users who prospectively reported the presence of aura in at least two treatment reports (reporting at least twice having aura) , OR:
- Users who prospectively reported the absence of aura in all of their reports, with at least two reports
Age in the registry: 8 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Theranica Bio-Electronics Ltd Coordinator of this site? Confirm its status | Netanya | Israel | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.