NCT06025357Completed
Effects of L-citrulline Supplementation on Vascular Function in Metabolic Syndrome
Effects of L-Citrulline Supplementation on Vascular Function During Fasted and Acute Hyperglycemia in Middle-aged and Older Women With Metabolic Syndrome
Source: ClinicalTrials.gov · Last updated 15 May 2025
Brief summary (registry, in English)
The objective of this project is to provide evidence that L-Citrulline (CIT) supplementation can improve vascular function in the fasted and acute hyperglycemia conditions in middle-aged and older women with metabolic syndrome.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 24 (actual)
- First submitted
- 27 Jul 2023
- Start date
- 1 Jan 2023
- Primary completion date
- 1 May 2024
- Lead sponsor
- Texas Tech University
- Diseases
- Obesity, High blood pressure
- NCT number
- NCT06025357
What you commit to
- Study type: Interventional
- Participants enrolled: 24
- From 1 Jan 2023 to the primary completion date, 1 May 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of medications and/or any supplements that may affect outcome variables (such as arginine-containing supplements, nitroglycerin, statin drugs, biguanides, insulin, beta blockers, statins, verapamil)
- Recent changes in medication (3 months)
Other illness
- Cardiovascular disease, diabetes (Type 1 or 2), and other metabolic or chronic diseases
Age
- \< 45 and \> 79 years of age
Other
- Systolic blood pressure ≥ 160 mmHg
- BMI \> 40 kg/m2
- Current smoking any tobacco use
- More than 7 alcoholic drinks/week of consumption
Who the study is looking for
- Must present at least 3 of the following 5 cardiometabolic risk factors
- Waist circumference ≥88 cm
- Fasting glucose between 100-125 mg/dL or HbA1c between 5.7-6.4%.
- Blood pressure ≥130 mm Hg
- Triglyceride ≥ 150 mg/dL
- HDL \<50 mg/dL
- The following are also inclusion criteria's:
- Women aged 45-79 years old
- Body mass index ≤ 39.9 kg/m2
- Sedentary (defined as \< 120 min/week of exercise)
- Abstain from any dietary supplements with vascular effects for one month prior to the beginning of the study and until participation in study has terminated.
Age in the registry: 45 years to 79 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| TTU Kinesiology and Sport Management Building Coordinator of this site? Confirm its status | Lubbock | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.