NCT06027671Recruiting
Structured Peer-delivered ART and Reentry Community Strategy
Structured Peer-delivered Antiretroviral Therapy (ART) and Reentry Community Strategy to Overcome Barriers to HIV Care Continuity During Community Re-entry From Incarceration in South Africa
Source: ClinicalTrials.gov · Last updated 2 Jun 2026
Brief summary (registry, in English)
The overarching goal of this study is to implement a transition community adherence club strategy (Full-SPARCS) for HIV-positive individuals transitioning from correctional to community settings in South Africa. The investigators seek to provide actionable findings to inform policy decisions to contribute to HIV care continuity with this population. The investigators note that effectiveness and scalability often conflict with intervention design; thus, the investigators have proposed testing whether a group approach is effective and the investigators will assess the costs of each component * To compare the effectiveness of Full-SPARCS to care as usual to achieve HIV RNA suppression 6 months following correctional facility release * To assess determinants of implementation of Full-SPARCS * To assess the scalability through costing and cost effectiveness analysis of Full-SPARCS
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 400 (estimated)
- First submitted
- 31 Aug 2023
- Start date
- 18 Nov 2024
- Primary completion date
- 1 Dec 2027
- Lead sponsor
- Johns Hopkins University
- Diseases
- HIV
- NCT number
- NCT06027671
What you commit to
- Study type: Interventional
- Planned participants: 400
- From 18 Nov 2024 to the primary completion date, 1 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Condition (severe cognitive dysfunction or mental illness) rendering the individual unable to provide informed consent.
Age
- \<18 years of age.
Other
- Unable to provide informed consent to participate in the study.
- Assessment by DCS health staff indicating that the individual requires a high intensity of care exceeding that which can be provided in a differentiated model of care setting.
- Not released from the correctional facility during the period of intervention delivery.
- Release to a region outside of Gauteng.
Who the study is looking for
- Incarcerated at one of the participating study enrolment sites, awaiting trial (un-sentenced) and sentenced individuals.
- Diagnosed with HIV and ART at the time of enrolment.
- Anticipated release or trial date within three months of study enrolment.
- Self-report expected to reside in an unrestricted environment within Ekurhuleni, Tshwane, or Johannesburg districts of Gauteng Province and within proximity to one of the SPARCS intervention sites (i.e., within 20km, 45-minute travel time, or two local taxi minibus rides)
- Willing to participate in study post-release follow-up activities and provide contact information for post-release follow-up.
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Aurum Institute - Head office Coordinator of this site? Confirm its status | Johannesburg | South Africa | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.